Comparative Assessment of Periodontal Status in Subjects with and Without Polycystic Ovary Syndrome and Its Correlation with Body Mass Index: A Cross-Sectional Study

Overview

Journal Indian J Community Med

Date 2023 Nov 16

PMID 37970163

Authors

Sarah Mariam

Amita Mali

Saif Khan

Neha Agrawal

Juhi Gupta

Najam Khalique

Affiliations

Soon will be listed here.

Abstract

New avenues for research have opened, which assess the influence of systemic disease on periodontium and vice versa. To find the correlation between polycystic ovary syndrome (PCOS) and periodontium by assessing clinical parameters [plaque index (PI), probing depth, periodontal disease index (PDI)] and the anthropological parameter [body mass index (BMI)] and to find the correlation between body mass index and periodontal disease index in subjects with and without PCOS. Sixty females comprising 30 with PCOS and 30 without PCOS were selected. Clinical, anthropological, and radiological assessment was done. Double blinding was incorporated. There was a statistically highly significant difference in mean age, mean PI, and mean PDI ( < 0.001) in PCOS group when compared to those without PCOS group by unpaired -test for inter-group analysis. A statistically significant difference was found in mean probing depth and mean BMI ( < 0.05) in PCOS group when compared to those without PCOS group by unpaired -test for inter-group analysis. No statistically significant correlation was found between mean PDI and mean BMI in PCOS and non-PCOS group subjects using Spearman's rank correlation. Women suffering from PCOS may be at a heightened risk for developing periodontal disease as our study re-establishes this association with respect to some periodontal parameters. With such a result, general practitioners/gynecologists can be encouraged to refer cases of PCOS to periodontists for early detection, prevention of periodontal disease, and maintenance of periodontal health.

References

Sam S, Dunaif A . Polycystic ovary syndrome: syndrome XX?. Trends Endocrinol Metab. 2003; 14(8):365-70. DOI: 10.1016/j.tem.2003.08.002. View

Baillargeon J, Iuorno M, Nestler J . Insulin sensitizers for polycystic ovary syndrome. Clin Obstet Gynecol. 2003; 46(2):325-40. DOI: 10.1097/00003081-200306000-00011. View

. Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome. Fertil Steril. 2004; 81(1):19-25. DOI: 10.1016/j.fertnstert.2003.10.004. View

Dursun E, Akalin F, Guncu G, Cinar N, Yazgan Aksoy D, Tozum T . Periodontal disease in polycystic ovary syndrome. Fertil Steril. 2010; 95(1):320-3. DOI: 10.1016/j.fertnstert.2010.07.1052. View

Ehrmann D, Barnes R, Rosenfield R, Cavaghan M, Imperial J . Prevalence of impaired glucose tolerance and diabetes in women with polycystic ovary syndrome. Diabetes Care. 1999; 22(1):141-6. DOI: 10.2337/diacare.22.1.141. View

Kelly C, Lyall H, Petrie J, Gould G, Connell J, Sattar N . Low grade chronic inflammation in women with polycystic ovarian syndrome. J Clin Endocrinol Metab. 2001; 86(6):2453-5. DOI: 10.1210/jcem.86.6.7580. View

Loos B, Craandijk J, Hoek F, Van der Velden U . Elevation of systemic markers related to cardiovascular diseases in the peripheral blood of periodontitis patients. J Periodontol. 2000; 71(10):1528-34. DOI: 10.1902/jop.2000.71.10.1528. View

Kershaw E, Flier J . Adipose tissue as an endocrine organ. J Clin Endocrinol Metab. 2004; 89(6):2548-56. DOI: 10.1210/jc.2004-0395. View

Akcali A, Bostanci N, Ozcaka O, Ozturk-Ceyhan B, Gumus P, Buduneli N . Association between polycystic ovary syndrome, oral microbiota and systemic antibody responses. PLoS One. 2014; 9(9):e108074. PMC: 4169459. DOI: 10.1371/journal.pone.0108074. View

10.

. Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) final report. Circulation. 2002; 106(25):3143-421. View

11.

Akcali A, Bostanci N, Ozcaka O, Gumus P, Ozturk-Ceyhan B, Tervahartiala T . Gingival Inflammation and Salivary or Serum Granulocyte-Secreted Enzymes in Patients With Polycystic Ovary Syndrome. J Periodontol. 2017; 88(11):1145-1152. DOI: 10.1902/jop.2017.170043. View

12.

Porwal S, Tewari S, Sharma R, Singhal S, Narula S . Periodontal status and high-sensitivity C-reactive protein levels in polycystic ovary syndrome with and without medical treatment. J Periodontol. 2014; 85(10):1380-9. DOI: 10.1902/jop.2014.130756. View

13.

Rahiminejad M, Moaddab A, Zaryoun H, Rabiee S, Moaddab A, Khodadoustan A . Comparison of prevalence of periodontal disease in women with polycystic ovary syndrome and healthy controls. Dent Res J (Isfahan). 2016; 12(6):507-12. PMC: 4696351. DOI: 10.4103/1735-3327.170547. View

14.

Saito T, Shimazaki Y, Kiyohara Y, Kato I, Kubo M, Iida M . Relationship between obesity, glucose tolerance, and periodontal disease in Japanese women: the Hisayama study. J Periodontal Res. 2005; 40(4):346-53. DOI: 10.1111/j.1600-0765.2005.00813.x. View