Perspectives of Cyanobacterial Cell Factories

Overview

Journal Photosynth Res

Publisher Springer

Date 2023 Nov 15

PMID 37966575

Authors

Anastasios Melis

Diego Alberto Hidalgo Martinez

Nico Betterle

Affiliations

Soon will be listed here.

Abstract

Cyanobacteria are prokaryotic photosynthetic microorganisms that can generate, in addition to biomass, useful chemicals and proteins/enzymes, essentially from sunlight, carbon dioxide, and water. Selected aspects of cyanobacterial production (isoprenoids and high-value proteins) and scale-up methods suitable for product generation and downstream processing are addressed in this review. The work focuses on the challenge and promise of specialty chemicals and proteins production, with isoprenoid products and biopharma proteins as study cases, and the challenges encountered in the expression of recombinant proteins/enzymes, which underline the essence of synthetic biology with these microorganisms. Progress and the current state-of-the-art in these targeted topics are emphasized.

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