Cataract Surgery Utilization in Parkinson's Disease: the English Longitudinal Survey on Ageing

Overview

Journal Graefes Arch Clin Exp Ophthalmol

Specialty Ophthalmology

Date 2023 Nov 10

PMID 37947822

Authors

Angela L Xu

Ali G Hamedani

Affiliations

Soon will be listed here.

Abstract

Purpose: Older adults with Alzheimer's disease are less likely to be offered cataract surgery than the general population, but these disparities have not been examined in the context of other neurodegenerative disorders such as Parkinson's disease (PD).

Methods: Using data from the English Longitudinal Study on Ageing (ELSA), an ongoing, longitudinal population-based survey of older adults in England, we examined the relationship between PD and cataract surgery among adults 50 and older. We used logistic regression to measure the association between PD and history of cataract surgery at baseline. In longitudinal analyses of subjects with no history of cataract surgery at time of enrollment, we used semiparametric, discrete-time proportional hazards models to model the incidence of cataract surgery as a function of PD and other time-dependent covariates. Models were adjusted for demographic variables, self-reported comorbidities, and measures of daily activity limitation.

Results: We included data from 19,241 eligible ELSA respondents, of whom 231 (1.2%) reported a diagnosis of PD. PD was positively associated with a history of self-reported cataract surgery at baseline (OR 3.66, 95% CI: 2.55-5.26), but this did not remain significant after adjusting for confounders (OR 1.22, 95% CI: 0.75-1.98). Among subjects with no history of cataract surgery at baseline, PD was also not associated with incident cataract surgery (adjusted HR 1.32, 95% CI: 0.86-2.02).

Conclusion: Unlike Alzheimer's disease, people with PD were no less likely to receive cataract surgery compared to those without PD.

References

Steptoe A, Breeze E, Banks J, Nazroo J . Cohort profile: the English longitudinal study of ageing. Int J Epidemiol. 2012; 42(6):1640-8. PMC: 3900867. DOI: 10.1093/ije/dys168. View

Lai S, Lin C, Liao K, Chang-Ou K . Increased risk of Parkinson's disease in cataract patients: a population-based cohort study. Parkinsonism Relat Disord. 2014; 21(1):68-71. DOI: 10.1016/j.parkreldis.2014.11.005. View

Foreman J, Xie J, Keel S, van Wijngaarden P, Taylor H, Dirani M . The validity of self-report of eye diseases in participants with vision loss in the National Eye Health Survey. Sci Rep. 2017; 7(1):8757. PMC: 5562791. DOI: 10.1038/s41598-017-09421-9. View

Coleman A, Stone K, Ewing S, Nevitt M, Cummings S, Cauley J . Higher risk of multiple falls among elderly women who lose visual acuity. Ophthalmology. 2004; 111(5):857-62. DOI: 10.1016/j.ophtha.2003.09.033. View

Patty L, Wu C, Torres M, Azen S, Varma R . Validity of self-reported eye disease and treatment in a population-based study: the Los Angeles Latino Eye Study. Ophthalmology. 2012; 119(9):1725-30. PMC: 3413787. DOI: 10.1016/j.ophtha.2012.02.029. View

Ehrlich J, Hassan S, Stagg B . Prevalence of Falls and Fall-Related Outcomes in Older Adults with Self-Reported Vision Impairment. J Am Geriatr Soc. 2018; 67(2):239-245. PMC: 6367006. DOI: 10.1111/jgs.15628. View

Crews J, Chou C, Stevens J, Saaddine J . Falls Among Persons Aged ≥65 Years With and Without Severe Vision Impairment - United States, 2014. MMWR Morb Mortal Wkly Rep. 2016; 65(17):433-7. DOI: 10.15585/mmwr.mm6517a2. View

Hamedani A, Abraham D, Maguire M, Willis A . Visual Impairment Is More Common in Parkinson's Disease and Is a Risk Factor for Poor Health Outcomes. Mov Disord. 2020; 35(9):1542-1549. PMC: 8183672. DOI: 10.1002/mds.28182. View

Lampela P, Tolppanen A, Kaarniranta K, Hokkinen K, Hartikainen S . Incidence of cataract surgeries in relation to diagnosis of Parkinson's disease. Arch Gerontol Geriatr. 2022; 104:104842. DOI: 10.1016/j.archger.2022.104842. View

10.

Levesque L, Hanley J, Kezouh A, Suissa S . Problem of immortal time bias in cohort studies: example using statins for preventing progression of diabetes. BMJ. 2010; 340:b5087. DOI: 10.1136/bmj.b5087. View

11.

Friedman D, Munoz B, Roche K, Massof R, Broman A, West S . Poor uptake of cataract surgery in nursing home residents: the Salisbury Eye Evaluation in Nursing Home Groups study. Arch Ophthalmol. 2005; 123(11):1581-7. DOI: 10.1001/archopht.123.11.1581. View

12.

Nowacka B, Lubinski W, Honczarenko K, Potemkowski A, Safranow K . Ophthalmological features of Parkinson disease. Med Sci Monit. 2014; 20:2243-9. PMC: 4238794. DOI: 10.12659/MSM.890861. View

13.

Javed U, McVeigh K, Scott N, Azuara-Blanco A . Cataract extraction and patient vision-related quality of life: a cohort study. Eye (Lond). 2015; 29(7):921-5. PMC: 4506347. DOI: 10.1038/eye.2015.70. View

14.

Pershing S, Henderson V, Bundorf M, Lu Y, Rahman M, Andrews C . Differences in Cataract Surgery Rates Based on Dementia Status. J Alzheimers Dis. 2019; 69(2):423-432. PMC: 10728498. DOI: 10.3233/JAD-181292. View

15.

Evans J, Fletcher A, Wormald R . Causes of visual impairment in people aged 75 years and older in Britain: an add-on study to the MRC Trial of Assessment and Management of Older People in the Community. Br J Ophthalmol. 2004; 88(3):365-70. PMC: 1772038. DOI: 10.1136/bjo.2003.019927. View

16.

Borm C, Smilowska K, de Vries N, Bloem B, Theelen T . How I do it: The Neuro-Ophthalmological Assessment in Parkinson's Disease. J Parkinsons Dis. 2019; 9(2):427-435. PMC: 6597980. DOI: 10.3233/JPD-181523. View

17.

Kim H, Leverenz J, Burdick D, Srivatsal S, Pate J, Hu S . Diagnostic Validation for Participants in the Washington State Parkinson Disease Registry. Parkinsons Dis. 2018; 2018:3719578. PMC: 6236556. DOI: 10.1155/2018/3719578. View

18.

Lee S, Lindquist K, Segal M, Covinsky K . Development and validation of a prognostic index for 4-year mortality in older adults. JAMA. 2006; 295(7):801-8. DOI: 10.1001/jama.295.7.801. View

19.

Hokkinen K, Kaarniranta K, Jamsen E, Lampela P, Hartikainen S, Tolppanen A . Incidence of cataract surgeries in people with and without Alzheimer's disease. Acta Ophthalmol. 2021; 100(1):68-73. DOI: 10.1111/aos.14896. View

20.

Wallace E, Segerstrom S, van Horne C, Schmitt F, Koehl L . Meta-Analysis of Cognition in Parkinson's Disease Mild Cognitive Impairment and Dementia Progression. Neuropsychol Rev. 2021; 32(1):149-160. DOI: 10.1007/s11065-021-09502-7. View