Ebola Virus Disease in Children: Epidemiology, Pathogenesis, Management, and Prevention

Overview

Journal Pediatr Res

Specialties Biology
Pediatrics

Date 2023 Oct 31

PMID 37903937

Authors

Katherine R Dobbs

Alyssa Lobb

Arlene E Dent

Affiliations

Soon will be listed here.

Abstract

Ebola disease is a severe disease with extremely high case-fatality rates ranging from 28-100%. Observations made during the 2013-2016 West African epidemic improved our understanding of the clinical course of Ebola disease and accelerated the study of therapeutic and preventative strategies. The epidemic also highlighted the unique challenges associated with providing optimal care for children during Ebola disease outbreaks. In this review, we outline current understanding of Ebola disease epidemiology, pathogenesis, management, and prevention, highlighting data pertinent to the care of children. IMPACT: In this review, we summarize recent advancements in our understanding of Ebola disease epidemiology, clinical presentation, and therapeutic and preventative strategies. We highlight recent data pertinent to the care of children and pregnant women and identify research gaps for this important emerging viral infection in children.

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