Recurrence of Large-Vessel Vasculitis Induced by Multiple Types of Granulocyte Colony-Stimulating Factor Preparation in Patient with Large-Cell Neuroendocrine Lung Carcinoma: A Case Report

Overview

Journal Case Rep Oncol

Publisher Karger

Specialty Oncology

Date 2023 Oct 30

PMID 37900825

Authors

Yurie Seto

Tadaaki Yamada

Masashi Egami

Takumi Sugimoto

Izumi Sato

Satomi Tanaka

Yusuke Chihara

Kenji Morimoto

Masahiro Iwasaku

Shinsaku Tokuda

Yoshiko Kaneko

Koichi Tamayama

Affiliations

Soon will be listed here.

Abstract

With the increased use of granulocyte colony-stimulating factor (G-CSF) preparations, there is concern about the increase in G-CSF-associated large-vessel vasculitis; however, there have been no previous reports of vasculitis caused by multiple types of G-CSF preparations. We experienced a case of drug-induced large-vessel vasculitis caused by two different G-CSF products, which was difficult to diagnose. When treating patients with a history of large-vessel vasculitis caused by pegfilgrastim, we need to pay attention to its recurrence when using other G-CSF preparations.

Citing Articles

Literature review analysis of aortitis induced by granulocyte-colony stimulating factor.

Zhao T, Xu H Front Pharmacol. 2025; 15:1487501.

PMID: 39744136 PMC: 11688214. DOI: 10.3389/fphar.2024.1487501.

Large-vessel vasculitis induced by pegfilgrastim and immune checkpoint inhibitor in a patient with small-cell lung cancer.

Shiraha K, Takigawa Y, Sato A, Fujiwara K, Matsuo Y, Goda M Respirol Case Rep. 2024; 12(2):e01291.

PMID: 38328632 PMC: 10848280. DOI: 10.1002/rcr2.1291.

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