Association Between Visceral Fat Area and Glycated Hemoglobin in Type 2 Diabetics: A Retrospective Study

Overview

Journal Diabetes Metab Syndr Obes

Publisher Dove Medical Press

Specialty Endocrinology

Date 2023 Oct 30

PMID 37900621

Authors

Beibei Luo

Wenbo Xu

Lei Feng

Jingyi Chen

Rui Shi

Huiying Cao

Affiliations

Soon will be listed here.

Abstract

Introduction: Obesity is a risk factor for the development of type 2 diabetes (T2DM) as well as its associated metabolic complications. Central obesity, characterized by an increased visceral fat area (VFA), is contributed to the development of T2DM. However, the relationship between VFA and HbA1c is not particularly clear.

Methods: A total of 3173 patients with T2DM participated in the study at the Metabolic Management Center (MMC), with anthropometric and biochemical measurements recorded. To examine the association between HbA1c and VFA, fitting curves were plotted, facilitating a comprehensive observation of their relationship.

Results: HbA1c was inversely associated with VFA (β -1.79, 95% CI -2.34~-1.24, P < 0.001). The fitted curve shows that VFA increased with the increase of HbA1c when it was less than 8.62%. When it was greater than 8.62%, VFA decreased as HbA1c increased. Using linear inflection point analysis, we found that its inflection point interval falls within 8.36%~8.88%.

Conclusion: VFA was positively associated with HbA1c in individuals with T2DM. Furthermore, the relationship between the two variables was an inverted U-shaped association.

Citing Articles

Association Between Visceral Obesity and Glycemic Control in Patients with Type 2 Diabetes Mellitus: A Retrospective Study.

Shang C, Yuan M, Wang Y, Wang Y, Bao W, Zeng S Diabetes Metab Syndr Obes. 2024; 17:2869-2880.

PMID: 39100969 PMC: 11298209. DOI: 10.2147/DMSO.S470836.

Association Between Serum Magnesium Levels and Glycemic Control in Type 2 Diabetes.

Luo B, Pan B, Zhao G, Li J, Sun L Diabetes Metab Syndr Obes. 2024; 17:2823-2829.

PMID: 39081371 PMC: 11288356. DOI: 10.2147/DMSO.S471787.

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