» Articles » PMID: 37900334

Investigation of Kidney Morphology and Somatotype Components in Early-Stage Kidney Patients

Overview
Specialty General Medicine
Date 2023 Oct 30
PMID 37900334
Authors
Affiliations
Soon will be listed here.
Abstract

Objectives: The aim of this study is to examine the kidney morphology and somatotype components of adult patients with early-stage chronic kidney disease (CKD).

Methods: The sample consisted of 46 individuals with early-stage CKD (26 men and 20 women, mean age=45.92±16.53 years). The pathological subjects were compared with a control group consisting of 46 healthy subjects (28 men and 18 women, mean age=41.96±11.48 years). The Heath-Carter method was used to determine somatotype components. Abdominal computed tomography (CT) of patients with Stage 2 CKD and healthy volunteers taken within the past 3 months was scanned to determine kidney morphology. Kidney measurements were performed on CTs (length, width, depth, and volume of kidney).

Results: Kidney patients (mean somatotype: 6.33-5.37-0.6) were less ectomorphic and more endomorphic than the controls (mean somatotype: 4.35-4.40-3.02). Moderate effect size (ES) was found in endomorphy (ES=0.87; p=0.035) and ectomorphy (ES=1.08; p=0.012) between groups. No significant difference was observed in the kidney morphology (ES=0.04-0.19; p>0.05).

Conclusion: In the early-stage CKD, kidney morphology may not be the distinguishing factor. On the other hand, patients differed significantly in terms of endomorph components. Being overweight can also be one of the negative findings for kidney disease. Somatotype classification could be a suitable tool for monitoring kidney disease.

References
1.
Okur A, Serin H, Zengin K, Erkoc M, Tanik S, Yildirim U . Relationship between kidney volume and body indexes in the Turkish population determined using ultrasonography. Int Braz J Urol. 2015; 40(6):816-22. DOI: 10.1590/S1677-5538.IBJU.2014.06.13. View

2.
Sharma K, Caroli A, Quach L, Petzold K, Bozzetto M, Serra A . Kidney volume measurement methods for clinical studies on autosomal dominant polycystic kidney disease. PLoS One. 2017; 12(5):e0178488. PMC: 5448775. DOI: 10.1371/journal.pone.0178488. View

3.
Johnson N, George J . Fitness versus fatness: moving beyond weight loss in nonalcoholic fatty liver disease. Hepatology. 2010; 52(1):370-81. DOI: 10.1002/hep.23711. View

4.
Levey A, Eckardt K, Tsukamoto Y, Levin A, Coresh J, Rossert J . Definition and classification of chronic kidney disease: a position statement from Kidney Disease: Improving Global Outcomes (KDIGO). Kidney Int. 2005; 67(6):2089-100. DOI: 10.1111/j.1523-1755.2005.00365.x. View

5.
Altun B, Suleymanlar G, Utas C, Arinsoy T, Ates K, Ecder T . Prevalence, awareness, treatment and control of hypertension in adults with chronic kidney disease in Turkey: results from the CREDIT study. Kidney Blood Press Res. 2012; 36(1):36-46. DOI: 10.1159/000339025. View