Recent Advances in the Development of Biomimetic Materials

Overview

Journal Gels

Date 2023 Oct 27

PMID 37888406

Authors

Maria G Ciulla

Alessio Massironi

Michela Sugni

Matthew A Ensign

Stefania Marzorati

Mahdi Forouharshad

Affiliations

Soon will be listed here.

Abstract

In this review, we focused on recent efforts in the design and development of materials with biomimetic properties. Innovative methods promise to emulate cell microenvironments and tissue functions, but many aspects regarding cellular communication, motility, and responsiveness remain to be explained. We photographed the state-of-the-art advancements in biomimetics, and discussed the complexity of a "bottom-up" artificial construction of living systems, with particular highlights on hydrogels, collagen-based composites, surface modifications, and three-dimensional (3D) bioprinting applications. Fast-paced 3D printing and artificial intelligence, nevertheless, collide with reality: How difficult can it be to build reproducible biomimetic materials at a real scale in line with the complexity of living systems? Nowadays, science is in urgent need of bioengineering technologies for the practical use of bioinspired and biomimetics for medicine and clinics.

Citing Articles

Hemostatic Antimicrobial Hydrogels Based on Silicon, Iron, Zinc, and Boron Glycerolates for Wound Healing Applications.

Khonina T, Alekseenko S, Shadrina E, Ganebnykh I, Mekhaev A, Larionov L Gels. 2024; 10(12).

PMID: 39727553 PMC: 11675389. DOI: 10.3390/gels10120795.

Biomineral-Based Composite Materials in Regenerative Medicine.

Kim S, Ki M, Han Y, Pack S Int J Mol Sci. 2024; 25(11).

PMID: 38892335 PMC: 11173312. DOI: 10.3390/ijms25116147.

Recent Advances in Biomimetics for the Development of Bio-Inspired Prosthetic Limbs.

Varaganti P, Seo S Biomimetics (Basel). 2024; 9(5).

PMID: 38786483 PMC: 11118077. DOI: 10.3390/biomimetics9050273.

Evolution of Hybrid Hydrogels: Next-Generation Biomaterials for Drug Delivery and Tissue Engineering.

Rana M, De la Hoz Siegler H Gels. 2024; 10(4).

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