Genetic Association Between Rs1695 in Glutathione S-transferase P1 and Risk of Periodontitis: a Pilot Study

Overview

Journal Mol Biol Res Commun

Specialty Molecular Biology

Date 2023 Oct 27

PMID 37886736

Authors

Rakshitha Vettri Saravanan

Anitha Pandi

Karthikeyan Murthykumar

Smiline Girija Aseervatham Selvi

Paramasivam Arumugam

Vijayashree Priyadharsini Jayaseelan

Affiliations

Soon will be listed here.

Abstract

The present study aims to determine the association between a genetic polymorphism of (rs1695) and the risk of periodontitis. This study used a cross-sectional design and included subjects from the South Indian population. A total of 100 individuals enrolled at Saveetha Dental College and Hospital, Tamil Nadu were included in this study. The participants were divided into control (n=50) and periodontitis (n=50) based on clinical examination. Blood samples were collected. Genotyping was performed using specific primers spanning the polymorphic site. The genotypic frequencies for the rs1695 polymorphism were not significantly different between cases and controls.

Citing Articles

Glutathione S-transferase M1, T1, and P1 polymorphisms and periodontitis in a Caucasian population: a case-control study.

Izakovicova P, Fassmann A, Dusek L, Holla L BMC Oral Health. 2024; 24(1):288.

PMID: 38419025 PMC: 10903033. DOI: 10.1186/s12903-024-04034-x.

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