Detection and Characterization of Novel Luchacoviruses, Genus , in Saliva and Feces of Meso-carnivores in the Northeastern United States

Overview

Journal J Virol

Publisher American Society for Microbiology

Date 2023 Oct 26

PMID 37882520

Authors

Ximena A Olarte-Castillo

Laura Plimpton

Holly McQueary

Yining Sun

Y Tina Yu

Sarah Cover

Amy N Richardson

Yuhan Jin

Jennifer K Grenier

Kevin J Cummings

Elizabeth Bunting

Maria Diuk-Wasser

David Needle

Krysten Schuler

Michael J Stanhope

Gary Whittaker

Laura B Goodman

Affiliations

Soon will be listed here.

Abstract

Several coronaviruses (CoVs) have been detected in domesticated, farmed, and wild meso-carnivores, causing a wide range of diseases and infecting diverse species, highlighting their important but understudied role in the epidemiology of these viruses. Assessing the viral diversity hosted in wildlife species is essential to understand their significance in the cross-species transmission of CoVs. Our focus here was on CoV discovery in meso-carnivores in the Northeast United States as a potential "hotspot" area with high density of humans and urban wildlife. This study identifies novel alphacoronaviruses circulating in multiple free-ranging wild and domestic species in this area and explores their potential epidemiological importance based on regions of the Spike gene, which are relevant for virus-host interactions.

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