Esthetic Effects and Color Stability of Resin Infiltration on Demineralized Enamel Lesions: A Systematic Review

Overview

Journal J Int Soc Prev Community Dent

Date 2023 Oct 25

PMID 37876578

Authors

Dayang Fadzlina Abang Ibrahim

Annapurny Venkiteswaran

Noren Nor Hasmun

Affiliations

Soon will be listed here.

Abstract

Aims And Objectives: The aim of this study was to systematically review the ability of resin infiltration to conceal demineralized enamel lesions to normal enamel translucency and to maintain color stability.

Materials And Methods: A literature search of PubMed, MEDLINE, Web of Science, and Scopus databases and a manual search of articles from 2009 to 2021 for randomized controlled trials (RCTs) and clinical efficacy trials (nonrandomized) were performed. Methodological quality and risk of bias (RoB) of included papers was assessed using Cochrane Collaboration Risk of Bias Tool 2.0 for RCTs and ROBINS-I (Risk Of Bias In Non-randomized Studies of Interventions) tool for nonrandomized studies.

Results: A total of 352 titles and abstracts were reviewed. Eight RCTs and three clinical efficiency studies were included in this review. The masking effects of the demineralized enamel lesion were reported immediately after resin infiltration, and the color stability of this material was up to 24 months, with no adverse effects noted. For RCTs, four studies were classified as "some concerns" and four were as "low RoB." For nonrandomized studies, all of the studies presented an overall moderate RoB.

Conclusion: Resin infiltration achieves the best esthetic outcomes compared with microabrasion and remineralization therapy. Color stability was achieved with this material for up to 24 months and no adverse effects were noted. Factors contributing to the esthetic outcomes of the resin include the elimination of the hypermineralized surface layer, the homogeneity of the resin itself, and polishing after resin infiltration. Longitudinal follow-up and improved control of confounding variables should characterize future high-quality systematic reviews.

Citing Articles

Impact of silica nanoparticles incorporation on the properties of resin infiltration: an in vitro study.

ElEmbaby A, Nassar A, Elawsya M BMC Oral Health. 2024; 24(1):1484.

PMID: 39654050 PMC: 11629512. DOI: 10.1186/s12903-024-05107-7.

References

Baafif H, Alibrahim I, Alotaibi S, Alharbi H, Shubaily M, Elkwatehy W . The Efficacy of Resin Infiltrant and Casein Phosphopeptide-amorphous Calcium Fluoride Phosphate in Treatment of White Spot Lesions (Comparative Study). J Int Soc Prev Community Dent. 2020; 10(4):438-444. PMC: 7523932. DOI: 10.4103/jispcd.JISPCD_483_19. View

Gu X, Yang L, Yang D, Gao Y, Duan X, Zhu X . Esthetic improvements of postorthodontic white-spot lesions treated with resin infiltration and microabrasion: . Angle Orthod. 2019; 89(3):372-377. PMC: 8117680. DOI: 10.2319/041218-274.1. View

Kim S, Kim E, Jeong T, Kim J . The evaluation of resin infiltration for masking labial enamel white spot lesions. Int J Paediatr Dent. 2011; 21(4):241-8. DOI: 10.1111/j.1365-263X.2011.01126.x. View

Morgan R, Thayer K, Santesso N, Holloway A, Blain R, Eftim S . Evaluation of the risk of bias in non-randomized studies of interventions (ROBINS-I) and the 'target experiment' concept in studies of exposures: Rationale and preliminary instrument development. Environ Int. 2018; 120:382-387. PMC: 9581061. DOI: 10.1016/j.envint.2018.08.018. View

Ou X, Zhao Y, Ci X, Zeng L . Masking white spots of enamel in caries lesions with a non-invasive infiltration technique in vitro. Genet Mol Res. 2014; 13(3):6912-9. DOI: 10.4238/2014.August.29.14. View

Torres P, Phan H, Bojorquez A, Garcia-Godoy F, Pinzon L . Minimally Invasive Techniques Used for Caries Management in Dentistry. A Review. J Clin Pediatr Dent. 2021; 45(4):224-232. DOI: 10.17796/1053-4625-45.4.2. View

Flemming J, Hannig C, Hannig M . Caries Management-The Role of Surface Interactions in De- and Remineralization-Processes. J Clin Med. 2022; 11(23). PMC: 9737279. DOI: 10.3390/jcm11237044. View

Methley A, Campbell S, Chew-Graham C, McNally R, Cheraghi-Sohi S . PICO, PICOS and SPIDER: a comparison study of specificity and sensitivity in three search tools for qualitative systematic reviews. BMC Health Serv Res. 2014; 14:579. PMC: 4310146. DOI: 10.1186/s12913-014-0579-0. View

Neuhaus K, Schlafer S, Lussi A, Nyvad B . Infiltration of natural caries lesions in relation to their activity status and acid pretreatment in vitro. Caries Res. 2012; 47(3):203-10. DOI: 10.1159/000345654. View

10.

Sterne J, Savovic J, Page M, Elbers R, Blencowe N, Boutron I . RoB 2: a revised tool for assessing risk of bias in randomised trials. BMJ. 2019; 366:l4898. DOI: 10.1136/bmj.l4898. View

11.

Knosel M, Eckstein A, Helms H . Durability of esthetic improvement following Icon resin infiltration of multibracket-induced white spot lesions compared with no therapy over 6 months: a single-center, split-mouth, randomized clinical trial. Am J Orthod Dentofacial Orthop. 2013; 144(1):86-96. DOI: 10.1016/j.ajodo.2013.02.029. View

12.

Page M, Moher D, Bossuyt P, Boutron I, Hoffmann T, Mulrow C . PRISMA 2020 explanation and elaboration: updated guidance and exemplars for reporting systematic reviews. BMJ. 2021; 372:n160. PMC: 8005925. DOI: 10.1136/bmj.n160. View

13.

Lo Giudice R, Lipari F, Puleio F, Alibrandi A, Lo Giudice F, Tama C . Spectrophotometric Evaluation of Enamel Color Variation Using Infiltration Resin Treatment of White Spot Lesions at One Year Follow-Up. Dent J (Basel). 2020; 8(2). PMC: 7344573. DOI: 10.3390/dj8020035. View

14.

Borges A, Caneppele T, Masterson D, Maia L . Is resin infiltration an effective esthetic treatment for enamel development defects and white spot lesions? A systematic review. J Dent. 2016; 56:11-18. DOI: 10.1016/j.jdent.2016.10.010. View

15.

Saccucci M, Corridore D, Di Carlo G, Bonucci E, Cicciu M, Vozza I . Assessment of Enamel Color Stability of Resins Infiltration Treatment in Human Teeth: A Systematic Review. Int J Environ Res Public Health. 2022; 19(18). PMC: 9517161. DOI: 10.3390/ijerph191811269. View

16.

Kannan A, Padmanabhan S . Comparative evaluation of Icon® resin infiltration and Clinpro™ XT varnish on colour and fluorescence changes of white spot lesions: a randomized controlled trial. Prog Orthod. 2019; 20(1):23. PMC: 6571438. DOI: 10.1186/s40510-019-0276-y. View

17.

Eckstein A, Helms H, Knosel M . Camouflage effects following resin infiltration of postorthodontic white-spot lesions in vivo: One-year follow-up. Angle Orthod. 2014; 85(3):374-80. PMC: 8612424. DOI: 10.2319/050914-334.1. View

18.

Tennert C, Suarez Machado L, Jaeggi T, Meyer-Lueckel H, Wierichs R . Posterior ceramic versus metal restorations: A systematic review and meta-analysis. Dent Mater. 2022; 38(10):1623-1632. DOI: 10.1016/j.dental.2022.08.002. View

19.

Hasmun N, Vettore M, Lawson J, Elcock C, Zaitoun H, Rodd H . Determinants of children's oral health-related quality of life following aesthetic treatment of enamel opacities. J Dent. 2020; 98:103372. DOI: 10.1016/j.jdent.2020.103372. View

20.

Youssef A, Farid M, Zayed M, Lynch E, Alam M, Kielbassa A . Improving oral health: a short-term split-mouth randomized clinical trial revealing the superiority of resin infiltration over remineralization of white spot lesions. Quintessence Int. 2020; 51(9):696-709. DOI: 10.3290/j.qi.a45104. View