Impact of Experiencing Multiple Vulnerabilities on Fetal Growth and Complications in Women with Hyperglycemia in Pregnancy

Overview

Journal BMC Pregnancy Childbirth

Publisher Biomed Central

Specialty Gynecology & Obstetrics

Date 2023 Oct 18

PMID 37853313

Authors

Helene Bihan

Charlotte Nachtargeale

Eric Vicaud

Meriem Sal

Narimane Berkane

Sara Pinto

Sopio Tatulashvili

Marion Fermaut

Lionel Carbillon

Emmanuel Cosson

Affiliations

Soon will be listed here.

Abstract

Background: In women with hyperglycemia in pregnancy living in France, psychosocial deprivation is associated with both earlier and greater exposure to the condition, as well as poorer maternofetal prognosis. We explored the impact of this and two other socioeconomic vulnerability indicators-food insecurity and poor language proficiency-on adherence to prenatal care and maternal and fetal outcomes.

Methods: In a socially deprived suburb of Paris, we selected women who delivered between 01/01/2012 and 31/12/2018 and received care (nurse, dietician, diabetologist evaluation, advice, regular follow-up to adjust insulin doses if requested) for hyperglycemia in pregnancy. We analyzed the associations between individual psychosocial deprivation, food insecurity, French language proficiency (variables assessed by individual questionnaires) and fetal growth (main outcome), as well as other core maternal and fetal outcomes.

Results: Among the 1,168 women included (multiethnic cohort, 19.3% of whom were Europeans), 56%, 17.9%, and 27.5% had psychosocial deprivation, food insecurity, and poor French language proficiency, respectively. Forty-three percent were prescribed insulin therapy. Women with more than one vulnerability had more consultations for diabetes. The rates for small (SGA), appropriate (AGA), and large-for-gestational-age (LGA) infant were 11.4%, 76.5% and 12.2%, respectively. These rates were similar in women with and without psychosocial deprivation, and in those with and without food insecurity. Interestingly, women with poor French language proficiency had a higher odds ratio of delivering a small- or large-for-gestational age infant than those with good proficiency.

Conclusion: We found similar pregnancy outcomes for women with hyperglycemia in pregnancy living in France, irrespective of whether or not they had psychosocial deprivation or food insecurity. Optimized single-center care with specialized follow-up could contribute to reduce inequalities in maternal and fetal outcomes in women with hyperglycemia in pregnancy.

Citing Articles

Hyperglycaemia in Pregnancy Is Less Frequent in Smokers: A French Observational Study of 15,801 Women.

Cosson E, Tatulashvili S, Vicaut E, Carbillon L, Bihan H, Rezgani I J Clin Med. 2024; 13(17).

PMID: 39274361 PMC: 11396654. DOI: 10.3390/jcm13175149.

Associations between food insecurity in high-income countries and pregnancy outcomes: A systematic review and meta-analysis.

Bell Z, Nguyen G, Andreae G, Scott S, Sermin-Reed L, Lake A PLoS Med. 2024; 21(9):e1004450.

PMID: 39255262 PMC: 11386426. DOI: 10.1371/journal.pmed.1004450.

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