Hepatic β-arrestins: Potential Roles in Liver Health and Disease

Overview

Journal Mol Biol Rep

Specialty Molecular Biology

Date 2023 Oct 16

PMID 37843713

Authors

Alzahraa Muhammad Eissa

Mohamed H Hassanin

Islam A A E H Ibrahim

Affiliations

Soon will be listed here.

Abstract

Β-arrestins are intracellular scaffolding proteins that have multifaceted roles in different types of disorders. In this review article, we gave a summary about the discovery, characterization and classification of these proteins and their intracellular functions. Moreover, this review article focused on the hepatic expression of β-arrestins and their hepatocellular distribution and function in each liver cell type. Also, we showed that β-arrestins are key regulators of distinct types of hepatic disorders. On the other hand, we addressed some important points that have never been studied before regarding the role of β-arrestins in certain types of hepatic disorders which needs more research efforts to cover.

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