Pituitary Stalk Interruption Syndrome: A Case Report

Pituitary stalk interruption syndrome (PSIS) is a rare congenital abnormality. It comprises the triad of thin or interrupted pituitary stalk, aplasia or hypoplasia of anterior pituitary gland, and absent or ectopic posterior pituitary gland. The patient usually presents with a spectrum of symptoms predominantly secondary to anterior pituitary hormonal deficiency. The etiology of this syndrome is not well-established but the genetic cause is considered to be the most common etiology. Early diagnosis is crucial in preventing and reducing morbidity. The prognosis is good if the condition is diagnosed early and the hormonal therapy is started promptly. The diagnosis of PSIS is primarily based on magnetic resonance imaging (MRI) findings.