» Articles » PMID: 37833652

Diagnosis and Management of Elevated Intracranial Pressure in the Emergency Department

Overview
Journal Int J Emerg Med
Publisher Biomed Central
Specialty Emergency Medicine
Date 2023 Oct 13
PMID 37833652
Authors
Affiliations
Soon will be listed here.
Abstract

Background: Elevated intracranial pressure is a devastating complication of catastrophic brain injury. Intracranial hypertension is commonly seen in neurologic injury secondary to traumatic brain injuries. Uncontrolled pressures can lead to permanent neurologic damage, but acute medical management is often overlooked when pursuing surgical management options that may not always be indicated.

Discussion: Traumatic brain injury is the leading cause of death in patients with severe neurologic injury. Diagnosing elevated intracranial pressures is imperative in initiating prompt treatment to reduce secondary central nervous system injury, morbidity, and mortality. Although the initial injury to the brain is typically irreversible, intracranial pressure control can assist in salvaging the remaining brain tissue from additional damage. We will discuss the initial medical and surgical management of traumatic brain injury to prevent further neurologic deterioration and reduce mortality.

Conclusion: Recent literature has reported several methods to detect elevated intracranial pressure easily and studies describing multiple treatment modalities. These investigations suggest that early detection and timely treatment of intracranial hypertension are beneficial in reducing mortality.

Citing Articles

Laser localization with soft‑channel minimally invasive surgery in cerebral hemorrhage.

Chen A, Peng J, Luo T, Cheng L, Wang Q, Su J Exp Ther Med. 2025; 29(3):47.

PMID: 39885906 PMC: 11775752. DOI: 10.3892/etm.2025.12797.


Neurological manifestations of encephalitic alphaviruses, traumatic brain injuries, and organophosphorus nerve agent exposure.

VanderGiessen M, de Jager C, Leighton J, Xie H, Theus M, Johnson E Front Neurosci. 2024; 18:1514940.

PMID: 39734493 PMC: 11671522. DOI: 10.3389/fnins.2024.1514940.


Global traumatic brain injury intracranial pressure: from monitoring to surgical decision.

Zhang D, Sheng Y, Wang C, Chen W, Shi X Front Neurol. 2024; 15:1423329.

PMID: 39355091 PMC: 11442239. DOI: 10.3389/fneur.2024.1423329.


Management of chimeric antigen receptor T (CAR-T) cell-associated toxicities.

Schroeder T, Martens T, Fransecky L, Valerius T, Schub N, Pott C Intensive Care Med. 2024; 50(9):1459-1469.

PMID: 39172238 PMC: 11377606. DOI: 10.1007/s00134-024-07576-4.


Outcome after Intracerebral Haemorrhage and Decompressive Craniectomy in Older Adults.

Kapapa T, Jesuthasan S, Schiller F, Schiller F, Oehmichen M, Woischneck D Neurol Int. 2024; 16(3):590-604.

PMID: 38804483 PMC: 11130851. DOI: 10.3390/neurolint16030044.

References
1.
Canac N, Jalaleddini K, Thorpe S, Thibeault C, Hamilton R . Review: pathophysiology of intracranial hypertension and noninvasive intracranial pressure monitoring. Fluids Barriers CNS. 2020; 17(1):40. PMC: 7310456. DOI: 10.1186/s12987-020-00201-8. View

2.
Pace J, Parry N, Vogt K, Hilsden R, Leeper R, Markova Z . A clinical prediction model for raised intracranial pressure in patients with traumatic brain injuries. J Trauma Acute Care Surg. 2018; 85(2):380-386. DOI: 10.1097/TA.0000000000001965. View

3.
Fernando S, Tran A, Cheng W, Rochwerg B, Taljaard M, Kyeremanteng K . Diagnosis of elevated intracranial pressure in critically ill adults: systematic review and meta-analysis. BMJ. 2019; 366:l4225. PMC: 6651068. DOI: 10.1136/bmj.l4225. View

4.
Cadena R, Shoykhet M, Ratcliff J . Emergency Neurological Life Support: Intracranial Hypertension and Herniation. Neurocrit Care. 2017; 27(Suppl 1):82-88. DOI: 10.1007/s12028-017-0454-z. View

5.
Tripathy S, Ahmad S . Raised Intracranial Pressure Syndrome: A Stepwise Approach. Indian J Crit Care Med. 2019; 23(Suppl 2):S129-S135. PMC: 6707500. DOI: 10.5005/jp-journals-10071-23190. View