Evaluation of and Implications for a Novel Hepatitis C E-consult Direct-to-treatment Pilot Program

Overview

Journal Sci Rep

Specialty Science

Date 2023 Oct 11

PMID 37821437

Authors

Neaka Z Mohtashemi

Crystal Y Teng

Jihane Benhammou

Tien Dong

Matthew Bidwell Goetz

Arpan Patel

Jenna Kawamoto

Debika Bhattacharya

Affiliations

Soon will be listed here.

Abstract

A Hepatitis C (HCV) e-Consult Direct-To-Treatment (DTT) program managed by midlevel providers was developed at the Veteran Affairs Greater Los Angeles Healthcare System (VAGLAHS) which provided remote referral and, in some, remote management of HCV. DTT patients were more likely to be initiated on HCV treatment compared to standard of care (SOC), lending support for similar programs of remote engagement in HCV care.

References

Kaufman H, Bull-Otterson L, Meyer 3rd W, Huang X, Doshani M, Thompson W . Decreases in Hepatitis C Testing and Treatment During the COVID-19 Pandemic. Am J Prev Med. 2021; 61(3):369-376. PMC: 8107198. DOI: 10.1016/j.amepre.2021.03.011. View

Hartl L, Jachs M, Bauer D, Simbrunner B, Chromy D, Binter T . HCV hotline facilitates Hepatitis C elimination during the COVID-19 pandemic. J Viral Hepat. 2022; 29(12):1062-1072. PMC: 9825935. DOI: 10.1111/jvh.13746. View

Hoyt K, Reynolds A . The Patient Perspective on Telemedicine. Clin Liver Dis (Hoboken). 2022; 19(4):167-170. PMC: 9053679. DOI: 10.1002/cld.1188. View

Yakovchenko V, Morgan T, Chinman M, Powell B, Gonzalez R, Park A . Mapping the road to elimination: a 5-year evaluation of implementation strategies associated with hepatitis C treatment in the veterans health administration. BMC Health Serv Res. 2021; 21(1):1348. PMC: 8684191. DOI: 10.1186/s12913-021-07312-4. View

Case L, Wright J, Ryan Y . Comparison of hepatitis C treatment outcomes between telehepatology and specialty care clinics in the era of direct-acting antivirals. J Telemed Telecare. 2019; 27(7):463-468. DOI: 10.1177/1357633X19885750. View

Hofmeister M, Rosenthal E, Barker L, Rosenberg E, Barranco M, Hall E . Estimating Prevalence of Hepatitis C Virus Infection in the United States, 2013-2016. Hepatology. 2018; 69(3):1020-1031. PMC: 6719781. DOI: 10.1002/hep.30297. View

Syed T, Cherian R, Lewis S, Sterling R . Telemedicine HCV treatment in department of corrections results in high SVR in era of direct-acting antivirals. J Viral Hepat. 2020; 28(1):209-212. DOI: 10.1111/jvh.13392. View

Belperio P, Chartier M, Ross D, Alaigh P, Shulkin D . Curing Hepatitis C Virus Infection: Best Practices From the U.S. Department of Veterans Affairs. Ann Intern Med. 2017; 167(7):499-504. DOI: 10.7326/M17-1073. View

Talal A, Andrews P, McLeod A, Chen Y, Sylvester C, Markatou M . Integrated, Co-located, Telemedicine-based Treatment Approaches for Hepatitis C Virus Management in Opioid Use Disorder Patients on Methadone. Clin Infect Dis. 2018; 69(2):323-331. DOI: 10.1093/cid/ciy899. View

10.

Amoako A, Ortiz-Paredes D, Engler K, Lebouche B, Klein M . Patient and provider perceived barriers and facilitators to direct acting antiviral hepatitis C treatment among priority populations in high income countries: A knowledge synthesis. Int J Drug Policy. 2021; 96:103247. DOI: 10.1016/j.drugpo.2021.103247. View

11.

Morrill J, Shrestha M, Grant R . Barriers to the treatment of hepatitis C. Patient, provider, and system factors. J Gen Intern Med. 2005; 20(8):754-8. PMC: 1490173. DOI: 10.1111/j.1525-1497.2005.0161.x. View

12.

Stephens D, Leston J, Terrault N, Gailloux K, Mera J, Essex W . An Evaluation of Hepatitis C Virus Telehealth Services Serving Tribal Communities: Patterns of Usage, Evolving Needs, and Barriers. J Public Health Manag Pract. 2019; :S97-S100. DOI: 10.1097/PHH.0000000000001061. View

13.

Dominitz J, Boyko E, Koepsell T, Heagerty P, Maynard C, Sporleder J . Elevated prevalence of hepatitis C infection in users of United States veterans medical centers. Hepatology. 2004; 41(1):88-96. DOI: 10.1002/hep.20502. View

14.

Gonzalez R, Park A, Yakovchenko V, Rogal S, Chartier M, Morgan T . HCV Elimination in the US Department of Veterans Affairs. Clin Liver Dis (Hoboken). 2021; 18(1):1-6. PMC: 8405054. DOI: 10.1002/cld.1150. View

15.

. Hepatitis C guidance: AASLD-IDSA recommendations for testing, managing, and treating adults infected with hepatitis C virus. Hepatology. 2015; 62(3):932-54. DOI: 10.1002/hep.27950. View

16.

Mcgowan C, Fried M . Barriers to hepatitis C treatment. Liver Int. 2012; 32 Suppl 1:151-6. PMC: 3955982. DOI: 10.1111/j.1478-3231.2011.02706.x. View

17.

Cooper C, Hatashita H, Corsi D, Parmar P, Corrin R, Garber G . Direct-Acting Antiviral Therapy Outcomes in Canadian Chronic Hepatitis C Telemedicine Patients. Ann Hepatol. 2017; 16(6):874-880. DOI: 10.5604/01.3001.0010.5277. View

18.

Rosato V, Nevola R, Conturso V, Perillo P, Mastrocinque D, Pappalardo A . Telemedicine Improves HCV Elimination among Italian People Who Use Drugs: An Innovative Therapeutic Model to Increase the Adherence to Treatment into Addiction Care Centers Evaluated before and during the COVID-19 Pandemic. Biology (Basel). 2022; 11(6). PMC: 9219716. DOI: 10.3390/biology11060800. View

19.

Beste L, Glorioso T, Ho P, Au D, Kirsh S, Todd-Stenberg J . Telemedicine Specialty Support Promotes Hepatitis C Treatment by Primary Care Providers in the Department of Veterans Affairs. Am J Med. 2016; 130(4):432-438.e3. DOI: 10.1016/j.amjmed.2016.11.019. View