» Articles » PMID: 37789103

Magnetic Particle Imaging-Guided Hyperthermia for Precise Treatment of Cancer: Review, Challenges, and Prospects

Overview
Publisher Springer
Date 2023 Oct 3
PMID 37789103
Authors
Affiliations
Soon will be listed here.
Abstract

Magnetic particle imaging (MPI) is a novel quantitative imaging technique using the nonlinear magnetization behavior of magnetic nanoparticles (MNPs) to determine their local concentration. Magnetic fluid hyperthermia (MFH) is a promising non-invasive therapy using the heating effects of MNPs. MPI-MFH is expected to enable real-time MPI guidance, localized MFH, and non-invasive temperature monitoring, which shows great potential for precise treatment of cancer. In this review, we introduce the fundamentals of MPI and MFH and their applications in the treatment of cancer. Also, we discuss the challenges and prospects of MPI-MFH.

Citing Articles

A Compendium of Magnetic Nanoparticle Essentials: A Comprehensive Guide for Beginners and Experts.

Amorim C Pharmaceutics. 2025; 17(1).

PMID: 39861783 PMC: 11768579. DOI: 10.3390/pharmaceutics17010137.


Advances in engineering nanoparticles for magnetic particle imaging (MPI).

Velazquez-Albino A, Imhoff E, Rinaldi-Ramos C Sci Adv. 2025; 11(2):eado7356.

PMID: 39772674 PMC: 11708890. DOI: 10.1126/sciadv.ado7356.


Integrable Magnetic Fluid Hyperthermia Systems for 3D Magnetic Particle Imaging.

Behrends A, Wei H, Neumann A, Friedrich T, Bakenecker A, Franke J Nanotheranostics. 2024; 8(2):163-178.

PMID: 38444740 PMC: 10911971. DOI: 10.7150/ntno.90360.

References
1.
Lee Y, Tan Y, Oon C . Molecular targeted therapy: Treating cancer with specificity. Eur J Pharmacol. 2018; 834:188-196. DOI: 10.1016/j.ejphar.2018.07.034. View

2.
Matsen C, Neumayer L . Breast cancer: a review for the general surgeon. JAMA Surg. 2013; 148(10):971-9. DOI: 10.1001/jamasurg.2013.3393. View

3.
Blumenschein G, Distefano A, Caderao J, Fristenberg B, Adams J, Schweichler L . Multimodality therapy for locally advanced and limited stage IV breast cancer: the impact of effective non-cross-resistance late-consolidation chemotherapy. Clin Cancer Res. 1999; 3(12 Pt 2):2633-7. View

4.
Baskar R, Lee K, Yeo R, Yeoh K . Cancer and radiation therapy: current advances and future directions. Int J Med Sci. 2012; 9(3):193-9. PMC: 3298009. DOI: 10.7150/ijms.3635. View

5.
Mohan R, Bortfeld T . Proton therapy: clinical gains through current and future treatment programs. Front Radiat Ther Oncol. 2011; 43:440-464. DOI: 10.1159/000322509. View