A Neuromusculoskeletal Modelling Approach to Bilateral Hip Mechanics Due to Unexpected Lateral Perturbations During Overground Walking

Overview

Journal BMC Musculoskelet Disord

Publisher Biomed Central

Specialties Orthopedics
Physiology

Date 2023 Oct 2

PMID 37784076

Authors

Yunchao Zhu

Ji Huang

Xin Ma

Wen-Ming Chen

Affiliations

Soon will be listed here.

Abstract

Background: Current studies on how external perturbations impact gait dynamics have primarily focused on the changes in the body's center of mass (CoM) during treadmill walking. The biomechanical responses, in particular to the multi-planar hip joint coordination, following perturbations in overground walking conditions are not completely known.

Methods: In this study, a customized gait-perturbing device was designed to impose controlled lateral forces onto the subject's pelvis during overground walking. The biomechanical responses of bilateral hips were simulated by subject-specific neuromusculoskeletal models (NMS) driven by in-vivo motion data, which were further evaluated by statistical parameter mapping (SPM) and muscle coactivation index (CI) analysis. The validity of the subject-specific NMS was confirmed through comparison with measured surface electromyographic signals.

Results: Following perturbations, the sagittal-plane hip motions were reduced for the leading leg by 18.39° and for the trailing leg by 8.23°, while motions in the frontal and transverse plane were increased, with increased hip abduction for the leading leg by 10.71° and external rotation by 9.06°, respectively. For the hip kinetics, both the bilateral hip joints showed increased abductor moments during midstance (20%-30% gait cycle) and decreased values during terminal stance (38%-48%). Muscle CI in both sagittal and frontal planes was significantly decreased for perturbed walking (p < 0.05), except for the leading leg in the sagittal plane.

Conclusion: The distinctive phase-dependent biomechanical response of the hip demonstrated its coordinated control strategy for balance recovery due to gait perturbations. And the changes in muscle CI suggested a potential mechanism for rapid and precise control of foot placement through modulation of joint stiffness properties. These findings obtained during actual overground perturbation conditions could have implications for the improved design of wearable robotic devices for balance assistance.

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References

Chander D, Cavatorta M . Multi-directional one-handed strength assessments using AnyBody Modeling Systems. Appl Ergon. 2017; 67:225-236. DOI: 10.1016/j.apergo.2017.09.015. View

Kuiken T, Lowery M, Stoykov N . The effect of subcutaneous fat on myoelectric signal amplitude and cross-talk. Prosthet Orthot Int. 2003; 27(1):48-54. DOI: 10.3109/03093640309167976. View

Hof A, Gazendam M, Sinke W . The condition for dynamic stability. J Biomech. 2004; 38(1):1-8. DOI: 10.1016/j.jbiomech.2004.03.025. View

Parvataneni K, Ploeg L, Olney S, Brouwer B . Kinematic, kinetic and metabolic parameters of treadmill versus overground walking in healthy older adults. Clin Biomech (Bristol). 2008; 24(1):95-100. DOI: 10.1016/j.clinbiomech.2008.07.002. View

Wang Y, Bhatt T, Liu X, Wang S, Lee A, Wang E . Can treadmill-slip perturbation training reduce immediate risk of over-ground-slip induced fall among community-dwelling older adults?. J Biomech. 2019; 84:58-66. PMC: 6361674. DOI: 10.1016/j.jbiomech.2018.12.017. View

Matjacic Z, Zadravec M, Olensek A . An effective balancing response to lateral perturbations at pelvis level during slow walking requires control in all three planes of motion. J Biomech. 2017; 60:79-90. DOI: 10.1016/j.jbiomech.2017.06.020. View

Hirjakova Z, Bizovska L, Bzduskova D, Hlavacka F, Janura M . Postural stability after treadmill and overground walking in young and elderly. Gait Posture. 2020; 80:84-89. DOI: 10.1016/j.gaitpost.2020.05.014. View

Alexander N, Schwameder H . Comparison of Estimated and Measured Muscle Activity During Inclined Walking. J Appl Biomech. 2015; 32(2):150-9. DOI: 10.1123/jab.2015-0021. View

Nagai K, Yamada M, Tanaka B, Uemura K, Mori S, Aoyama T . Effects of balance training on muscle coactivation during postural control in older adults: a randomized controlled trial. J Gerontol A Biol Sci Med Sci. 2012; 67(8):882-9. DOI: 10.1093/gerona/glr252. View

10.

McAndrew Young P, Wilken J, Dingwell J . Dynamic margins of stability during human walking in destabilizing environments. J Biomech. 2012; 45(6):1053-9. PMC: 3321251. DOI: 10.1016/j.jbiomech.2011.12.027. View

11.

Chambers A, Cham R . Slip-related muscle activation patterns in the stance leg during walking. Gait Posture. 2006; 25(4):565-72. DOI: 10.1016/j.gaitpost.2006.06.007. View

12.

Wu G, van der Helm F, Veeger H, Makhsous M, Van Roy P, Anglin C . ISB recommendation on definitions of joint coordinate systems of various joints for the reporting of human joint motion--Part II: shoulder, elbow, wrist and hand. J Biomech. 2005; 38(5):981-992. DOI: 10.1016/j.jbiomech.2004.05.042. View

13.

Hak L, Houdijk H, Steenbrink F, Mert A, van der Wurff P, Beek P . Speeding up or slowing down?: Gait adaptations to preserve gait stability in response to balance perturbations. Gait Posture. 2012; 36(2):260-4. DOI: 10.1016/j.gaitpost.2012.03.005. View

14.

Chen Z, Zhang X, Ardestani M, Wang L, Liu Y, Lian Q . Prediction of in vivo joint mechanics of an artificial knee implant using rigid multi-body dynamics with elastic contacts. Proc Inst Mech Eng H. 2014; 228(6):564-575. DOI: 10.1177/0954411914537476. View

15.

Hof A, Duysens J . Responses of human hip abductor muscles to lateral balance perturbations during walking. Exp Brain Res. 2013; 230(3):301-10. DOI: 10.1007/s00221-013-3655-5. View

16.

Kubinski S, McQueen C, Sittloh K, Dean J . Walking with wider steps increases stance phase gluteus medius activity. Gait Posture. 2014; 41(1):130-5. PMC: 4268431. DOI: 10.1016/j.gaitpost.2014.09.013. View

17.

Abbasi A, Yazdanbakhsh F, Tazji M, Ataabadi P, Svoboda Z, Nazarpour K . A comparison of coordination and its variability in lower extremity segments during treadmill and overground running at different speeds. Gait Posture. 2020; 79:139-144. DOI: 10.1016/j.gaitpost.2020.04.022. View

18.

De Pieri E, Romkes J, Wyss C, Brunner R, Viehweger E . Altered Muscle Contributions are Required to Support the Stance Limb During Voluntary Toe-Walking. Front Bioeng Biotechnol. 2022; 10:810560. PMC: 9036482. DOI: 10.3389/fbioe.2022.810560. View

19.

Robinovitch S, Feldman F, Yang Y, Schonnop R, Leung P, Sarraf T . Video capture of the circumstances of falls in elderly people residing in long-term care: an observational study. Lancet. 2012; 381(9860):47-54. PMC: 3540102. DOI: 10.1016/S0140-6736(12)61263-X. View

20.

Inacio M, Creath R, Rogers M . Low-dose hip abductor-adductor power training improves neuromechanical weight-transfer control during lateral balance recovery in older adults. Clin Biomech (Bristol). 2018; 60:127-133. PMC: 6293473. DOI: 10.1016/j.clinbiomech.2018.10.018. View