» Articles » PMID: 37768629

Predictors of Mental Health Outcomes of Three Refugee Groups in an Advocacy-based Intervention: A Precision Medicine Perspective

Overview
Specialty Psychology
Date 2023 Sep 28
PMID 37768629
Authors
Affiliations
Soon will be listed here.
Abstract

Objective: Precision medicine is an area with great potential for mental health, but has made limited gains prognostically in predicting effective treatments. For refugees exposed to violence, culture may be a crucial factor in predicting treatment outcomes.

Method: For this study, 290 participants from three regions (Afghanistan, the Great Lakes region of Africa, and Iraq and Syria) participated in a randomized controlled trial of an advocacy-based intervention. Emotional distress symptoms were measured prior to intervention, midintervention (3 months), postintervention (6 months), and follow-up (6 months after the end of intervention). Number of traumatic events, resource access, social support, and English proficiency were tested for potential predictive effects on intervention outcome.

Results: Multilevel generalized linear models revealed that Afghans' ( = -0.259, = 0.108, = .013), and Great Lakes Africans' ( = -0.116, = 0.057, = .042) emotional distress symptoms improved as a function of the intervention, while Iraqis and Syrians showed no intervention effects. For Afghans, English proficiency ( = -0.453, = 0.157, < .01) and social support ( = -0.179, = 0.086, = .037) were most strongly correlated to emotional distress, while for Africans, resource access ( = -0.483, = 0.082, < .001) and social support ( = -0.100, = 0.048, = .040) were the strongest predictors of emotional distress.

Conclusions: Response to advocacy-based interventions and active ingredients may be influenced by culture; findings have implications for refugees and precision medicine. (PsycInfo Database Record (c) 2024 APA, all rights reserved).

Citing Articles

From Serendipity to Precision: Integrating AI, Multi-Omics, and Human-Specific Models for Personalized Neuropsychiatric Care.

Tanaka M Biomedicines. 2025; 13(1).

PMID: 39857751 PMC: 11761901. DOI: 10.3390/biomedicines13010167.


War exposure, daily stressors, and mental health 15 years on: implications of an ecological framework for addressing the mental health of conflict-affected populations.

Miller K, Rasmussen A Epidemiol Psychiatr Sci. 2024; 33:e78.

PMID: 39659218 PMC: 11669807. DOI: 10.1017/S2045796024000830.

References
1.
Forman E, Shaw J, Goetter E, Herbert J, Park J, Yuen E . Long-term follow-up of a randomized controlled trial comparing acceptance and commitment therapy and standard cognitive behavior therapy for anxiety and depression. Behav Ther. 2012; 43(4):801-11. DOI: 10.1016/j.beth.2012.04.004. View

2.
Kuhlemeier A, Desai Y, Tonigan A, Witkiewitz K, Jaki T, Hsiao Y . Applying methods for personalized medicine to the treatment of alcohol use disorder. J Consult Clin Psychol. 2021; 89(4):288-300. PMC: 8284918. DOI: 10.1037/ccp0000634. View

3.
Perera S, Gavian M, Frazier P, Johnson D, Spring M, Westermeyer J . A longitudinal study of demographic factors associated with stressors and symptoms in African refugees. Am J Orthopsychiatry. 2013; 83(4):472-82. DOI: 10.1111/ajop.12047. View

4.
Miller K, Rasmussen A . War exposure, daily stressors, and mental health in conflict and post-conflict settings: bridging the divide between trauma-focused and psychosocial frameworks. Soc Sci Med. 2009; 70(1):7-16. DOI: 10.1016/j.socscimed.2009.09.029. View

5.
Sundvall M, Titelman D, DeMarinis V, Borisova L, Cetrez O . Safe but isolated - an interview study with Iraqi refugees in Sweden about social networks, social support, and mental health. Int J Soc Psychiatry. 2020; 67(4):351-359. DOI: 10.1177/0020764020954257. View