Indocyanine Green (ICG) and Colorectal Surgery: A Literature Review on Qualitative and Quantitative Methods of Usage

Overview

Journal Medicina (Kaunas)

Publisher MDPI

Specialty General Medicine

Date 2023 Sep 28

PMID 37763651

Authors

Laurentiu Simion

Sinziana Ionescu

Elena Chitoran

Vlad Rotaru

Ciprian Cirimbei

Octavia-Luciana Madge

Alin Codrut Nicolescu

Bogdan Tanase

Irinel-Gabriel Dicu-Andreescu

Denisa Mihaela Dinu

Dan Cristian Luca

Dana Lucia Stanculeanu

Adelina Silvana Gheorghe

Daniela Zob

Marian Marincas

Affiliations

Soon will be listed here.

Abstract

: Due to its many benefits, indocyanine green (ICG) has gained progressive popularity in operating rooms (ORs) globally. This literature review examines its qualitative and quantitative usage in surgical treatment. : Relevant terms were searched in five international databases (1. Pubmed, 2. Sciencedirect, 3. Scopus, 4. Oxfordjournals, 5. Reaxys) for a comprehensive literature review. The main benefits of using ICG in colorectal surgery are: intraoperative fluorescence angiography; fluorescence-guided lymph node involvement detection and the sentinel technique; the fluorescent emphasis of a minute liver tumour, counting just 200 tumour cells; facilitation of fistula diagnosis; and tumour tattooing. This methodology can also be used with quantitative characteristics such as maximum intensity, relative maximum intensity, and in-flow parameters such as time-to-peak, slope, and t1/2max. This article concludes that fluorescence surgery with ICG and near-infrared (NIR) light is a relatively new technology that improves anatomical and functional information, allowing more comprehensive and safer tumour removal and the preservation of important structures.

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