Relationship Between Prostate Inflammation and Periodontal Disease-A Systematic Review and Meta-Analysis

Overview

Journal J Clin Med

Specialty General Medicine

Date 2023 Sep 28

PMID 37763009

Authors

Pablo Ortiz de Urbina Comeron

Alvaro Zubizarreta-Macho

Ana Belen Lobo Galindo

Jose Maria Montiel-Company

Maria-Fernanda Lorenzo-Gomez

Javier Flores Fraile

Affiliations

Soon will be listed here.

Abstract

Materials And Methods: A systematic literature review and meta-analysis of longitudinal observational cohort and case-control studies that evaluated the odds ratio or hazard ratio and confidence interval was undertaken based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) recommendations (2020). A total of four databases were consulted in the literature search: PubMed-Medline, Scopus, Embase, and Web of Science. After eliminating duplicated articles and applying the inclusion criteria, seven articles were selected for the qualitative and quantitative analyses.

Results: Four observational cohort studies and three observational cohort case-control studies were included in the meta-analysis. The four observational cohort studies were combined using the random effects model to estimate a hazard ratio of 1.32 with a confidence interval of 95% between 0.87 and 1.77. The meta-analysis presented high heterogeneity (Q test = 56.1; value < 0.001; I = 94.9%). Moreover, the three observational case-control studies were combined using the random effects model to estimate an odds ratio of 1.62 with a confidence interval of 95% between 1.41 and 1.84. The meta-analysis presented high heterogeneity (Q test = 1.07; value = 0.782; I = 0%).

Conclusions: The incidence of periodontal disease does not increase the risk of the incidence of prostate inflammation.

Citing Articles

Chronic Periodontitis as a Risk Factor for Benign Prostatic Hyperplasia: A Cohort Study.

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Association between periodontal disease and systemic diseases: a cross-sectional analysis of current evidence.

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