Magnetic Resonance Volumetric Quantification of Vestibular Endolymphatic Hydrops in Patients with Unilateral Definite Meniere's Disease Using 3D Inversion Recovery with Real Reconstruction (3D-REAL-IR) Sequence

Overview

Journal J Clin Med

Specialty General Medicine

Date 2023 Sep 28

PMID 37762906

Authors

Victor Suarez-Vega

Raquel Manrique-Huarte

Pablo Dominguez

Melissa Blanco

Alberto Alonso-Burgos

Nicolas Perez-Fernandez

Affiliations

Soon will be listed here.

Abstract

Background: The 3D-REAL-IR MRI sequence allows for an in vivo visualization of endolymphatic hydrops. Qualitative assessment methods of the severity of vestibular and cochlear hydrops are the most commonly used.

Methods: A quantitative volumetric measurement of vestibular EH in patients with definite unilateral Ménière's disease using the 3D-REAL-IR sequence and the calculation of the endolymphatic ratio (ELR) was intended.

Results: Volumetric calculations of the vestibules, vestibular endolymph and vestibular ELR are performed in 96 patients with unilateral Ménière's disease and correlated with classic qualitative grading scales.

Conclusions: Quantitative volumetric measurement of vestibular hydrops using the 3D-REAL-IR sequence is feasible and reproducible in daily clinical practice. Vestibular ELR values exceeding 60% defined radiologically significant vestibular hydrops, while values below 30% defined radiologically non-significant vestibular hydrops.

Citing Articles

Is endolymphatic hydrops, as detected in MRI, a truly cochleocentric finding?.

Alvarez De Linera-Alperi M, Dominguez P, Blanco-Pareja M, Menendez Fernandez-Miranda P, Manrique-Huarte R, Liano G Front Neurol. 2024; 15:1477282.

PMID: 39687399 PMC: 11646843. DOI: 10.3389/fneur.2024.1477282.

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