Exploring the Effect of Pain Sensitive Questionnaire on Guiding Intravenous Analgesia After Cesarean Section: A Randomised Double Blind Controlled Trial

Overview

Journal J Pain Res

Publisher Dove Medical Press

Date 2023 Sep 25

PMID 37744183

Authors

Shuxin Liu

Siqi Liu

Dengfeng Gu

Xiaona Zhao

Hong Zhang

Chao Deng

Yajuan Gu

Affiliations

Soon will be listed here.

Abstract

Objective: This study investigates the effect of the Pain Sensitivity Questionnaire (PSQ) in guiding patient controlled intravenous analgesia (PCIA) on postoperative analgesia in women undergoing cesarean section.

Methods: A total of 160 women who were to undergo a cesarean section under combined spinal and epidural anaesthesia were included in this study. Women with a preoperative PSQ <4 were randomly divided into a low pain-sensitive control group (LC group), and a low pain-sensitive observation group (LO group), and women with preoperative PSQ >6 were randomly divided into a high pain-sensitive control group (HC group) and a high pain-sensitive observation group (HO group). After the surgery, patients received the pump butorphanol concentration was 3.5 µg·kg·h in the LC and HC groups, 3.0 µg·kg·h in the LO group and 4.0 µg·kg·h in the HO group.To compare the analgesic effects of postoperative PCIA and postoperative recovery in women.

Results: Wound pain and uterine contraction pain VAS scores at rest and activity were significantly lower in the LC group than in the LO group at 4 and 8 h postoperatively (P<0.05). Similarly, wound pain and uterine contraction pain VAS scores at rest and activity were significantly lower in the HO group than in the HC group at 8, 12, and 24 h postoperatively (P<0.05). The Ramsay scores were significantly higher in the LC than in the LO groups at 4, 8, 12, 24, and 48 h postoperatively (P<0.05), but there was no statistically significant difference between the Ramsay scores in the HC group and the HO group. There was no statistical difference in any of the post-operative recoveries (P>0.05).

Conclusion: Compared to the weight-based postoperative PCIA, the PSQ-based postoperative PCIA has better analgesic effects and can improve maternal satisfaction with postoperative analgesia.

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References

Commiskey S, Fan L, Ho I, Rockhold R . Butorphanol: effects of a prototypical agonist-antagonist analgesic on kappa-opioid receptors. J Pharmacol Sci. 2005; 98(2):109-16. DOI: 10.1254/jphs.crj05001x. View

Quan X, Fong D, Leung A, Liao Q, Ruscheweyh R, Chau P . Validation of the Mandarin Chinese Version of the Pain Sensitivity Questionnaire. Pain Pract. 2017; 18(2):180-193. DOI: 10.1111/papr.12587. View

Yadav J, Chandra Regmi M, Basnet P, Guddy K, Bhattarai B, Poudel P . Butorphanol in Labour Analgesia. JNMA J Nepal Med Assoc. 2019; 56(214):940-944. PMC: 8827606. View

Smith C, Collins C, Levett K, Armour M, Dahlen H, Tan A . Acupuncture or acupressure for pain management during labour. Cochrane Database Syst Rev. 2020; 2:CD009232. PMC: 7007200. DOI: 10.1002/14651858.CD009232.pub2. View

Ruscheweyh R, Verneuer B, Dany K, Marziniak M, Wolowski A, Colak-Ekici R . Validation of the pain sensitivity questionnaire in chronic pain patients. Pain. 2012; 153(6):1210-1218. DOI: 10.1016/j.pain.2012.02.025. View

Ruscheweyh R, Marziniak M, Stumpenhorst F, Reinholz J, Knecht S . Pain sensitivity can be assessed by self-rating: Development and validation of the Pain Sensitivity Questionnaire. Pain. 2009; 146(1-2):65-74. DOI: 10.1016/j.pain.2009.06.020. View

Chi X, Li M, Mei W, Liao M . Comparison of patient-controlled intravenous analgesia with sufentanil versus tramadol in post-cesarean section pain management and lactation after general anesthesia - a prospective, randomized, double-blind, controlled study. J Pain Res. 2017; 10:1521-1527. PMC: 5505163. DOI: 10.2147/JPR.S137799. View

Sutton C, Carvalho B . Optimal Pain Management After Cesarean Delivery. Anesthesiol Clin. 2017; 35(1):107-124. DOI: 10.1016/j.anclin.2016.09.010. View

Du B, Song Z, Wang K, Zhang H, Xu F, Zou Z . Butorphanol prevents morphine-induced pruritus without increasing pain and other side effects: a systematic review of randomized controlled trials. Can J Anaesth. 2013; 60(9):907-17. DOI: 10.1007/s12630-013-9989-4. View

10.

Ding X, Luo Y, Shi L, Liu C, Yan Z . Butorphanol in combination with dexmedetomidine provides efficient pain management in adult burn patients. Burns. 2021; 47(7):1594-1601. DOI: 10.1016/j.burns.2020.12.025. View

11.

Tuna T, Van Obbergh L, Van Cutsem N, Engelman E . Usefulness of the pain sensitivity questionnaire to discriminate the pain behaviour of chronic pain patients. Br J Anaesth. 2018; 121(3):616-622. DOI: 10.1016/j.bja.2018.04.042. View

12.

Sharpe E, Molitor R, Arendt K, Torbenson V, Olsen D, Johnson R . Intrathecal Morphine versus Intrathecal Hydromorphone for Analgesia after Cesarean Delivery: A Randomized Clinical Trial. Anesthesiology. 2020; 132(6):1382-1391. PMC: 8754417. DOI: 10.1097/ALN.0000000000003283. View

13.

Grundstrom H, Larsson B, Arendt-Nielsen L, Gerdle B, Kjolhede P . Associations between pain thresholds for heat, cold and pressure, and Pain Sensitivity Questionnaire scores in healthy women and in women with persistent pelvic pain. Eur J Pain. 2019; 23(9):1631-1639. DOI: 10.1002/ejp.1439. View

14.

Sun S, Guo Y, Wang T, Huang S . Analgesic Effect Comparison Between Nalbuphine and Sufentanil for Patient-Controlled Intravenous Analgesia After Cesarean Section. Front Pharmacol. 2020; 11:574493. PMC: 7751695. DOI: 10.3389/fphar.2020.574493. View

15.

McNicol E, Ferguson M, Hudcova J . Patient controlled opioid analgesia versus non-patient controlled opioid analgesia for postoperative pain. Cochrane Database Syst Rev. 2015; (6):CD003348. PMC: 7387354. DOI: 10.1002/14651858.CD003348.pub3. View

16.

Johnson C . Measuring Pain. Visual Analog Scale Versus Numeric Pain Scale: What is the Difference?. J Chiropr Med. 2009; 4(1):43-4. PMC: 2647033. DOI: 10.1016/S0899-3467(07)60112-8. View

17.

Braten L, Gjefsen E, Gervin K, Pripp A, Skouen J, Schistad E . Cytokine Patterns as Predictors of Antibiotic Treatment Effect in Chronic Low Back Pain with Modic Changes: Subgroup Analyses of a Randomized Trial (AIM Study). J Pain Res. 2023; 16:1713-1724. PMC: 10224727. DOI: 10.2147/JPR.S406079. View

18.

Seringec Akkececi N, Oksuz G, Urfalioglu A, Gunesacar R, Bakacak M, Arslan M . Preoperative Serum Leptin Level Is Associated with Preoperative Pain Threshold and Postoperative Analgesic Consumption in Patients Undergoing Cesarean Section. Med Princ Pract. 2019; 28(4):333-340. PMC: 6639575. DOI: 10.1159/000500556. View

19.

Wang Y, Fang X, Liu C, Ma X, Song Y, Yan M . Impact of Intraoperative Infusion and Postoperative PCIA of Dexmedetomidine on Early Breastfeeding After Elective Cesarean Section: A Randomized Double-Blind Controlled Trial. Drug Des Devel Ther. 2020; 14:1083-1093. PMC: 7073426. DOI: 10.2147/DDDT.S241153. View

20.

Melotti R, Ruscheweyh R, Pramstaller P, Hicks A, Pattaro C . Structural Consistency of the Pain Sensitivity Questionnaire in the Cooperative Health Research In South Tyrol (CHRIS) Population-Based Study. J Pain. 2018; 19(12):1424-1434. DOI: 10.1016/j.jpain.2018.06.007. View