Cue-reactivity Targeted Smoking Cessation Intervention in Individuals with Tobacco Use Disorder: a Scoping Review

Overview

Journal Front Psychiatry

Specialty Psychiatry

Date 2023 Sep 25

PMID 37743997

Authors

Miaoling Luo

Quan Gan

Yu Fu

Zhuangfei Chen

Affiliations

Soon will be listed here.

Abstract

Objectives: Cue-reactivity is a critical step leading to the emergence of addictive psychology and the triggering of addictive behaviors within the framework of addiction theory and is considered a significant risk factor for addiction-related behaviors. However, the effect of cue-reactivity targeted smoking cessation intervention and the cue-reactivity paradigms used in the randomized controlled trials varies, which introduces more heterogeneity and makes a side-by-side comparison of cessation responses difficult. Therefore, the scoping review aims to integrate existing research and identify evidence gaps.

Methods: We searched databases in English (PubMed and Embase) and Chinese (CNKI and Wanfang) using terms synonymous with 'cue' and 'tobacco use disorder (TUD)' to April 2023, and via hand-searching and reference screening of included studies. Studies were included if they were randomized controlled trials taking cue-reactivity as an indicator for tobacco use disorder (TUD) defined by different kinds of criteria.

Results: Data were extracted on each study's country, population, methods, timeframes, outcomes, cue-reactivity paradigms, and so on. Of the 2,944 literature were retrieved, 201 studies met the criteria and were selected for full-text screening. Finally, 67 pieces of literature were selected for inclusion and data extraction. The results mainly revealed that non-invasive brain stimulation and exercise therapy showed a trend of greater possibility in reducing subjective craving compared to the remaining therapies, despite variations in the number of research studies conducted in each category. And cue-reactivity paradigms vary in materials and mainly fall into two main categories: behaviorally induced craving paradigm or visually induced craving paradigm.

Conclusion: The current studies are still inadequate in terms of comparability due to their heterogeneity, cue-reactivity can be conducted in the future by constructing a standard library of smoking cue materials. Causal analysis is suggested in order to adequately screen for causes of addiction persistence, and further explore the specific objective cue-reactivity-related indicators of TUD.

Citing Articles

Isradipine augmentation of virtual reality cue exposure therapy for tobacco craving: a triple-blind randomized controlled trial.

Young C, Papini S, Minami H, Morikawa H, Otto M, Roache J Neuropsychopharmacology. 2024; 49(11):1711-1718.

PMID: 38789642 PMC: 11399233. DOI: 10.1038/s41386-024-01872-9.

Effects of brief mindfulness training on smoking cue-reactivity in tobacco use disorder: Study protocol for a randomized controlled trial.

Cheng L, Luo M, Ge J, Fu Y, Gan Q, Chen Z PLoS One. 2024; 19(4):e0299797.

PMID: 38648252 PMC: 11034654. DOI: 10.1371/journal.pone.0299797.

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