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Targeting Metacognitive Change Mechanisms in Acute Inpatients with Psychotic Symptoms: Feasibility and Acceptability of a Modularized Group Intervention

Overview
Specialties Neurology
Psychiatry
Date 2023 Sep 23
PMID 37741946
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Abstract

Emerging evidence suggests the usefulness of psychological interventions targeting metacognitive change mechanisms in patients experiencing psychosis. Although many of these patients are treated in acute psychiatric contexts, only few studies have adapted such interventions for acute inpatient settings. The present study aimed to assess the feasibility, acceptability, and preliminary clinical outcomes of a novel modularized group intervention focusing on different aspects of metacognitive change mechanisms. In particular, the intervention aims to reduce patients' acute symptoms by enhancing cognitive insight and to relieve distress via cognitive defusion (i.e. coping). A sample of 37 participants with acute psychosis received up to nine sessions of the intervention. Baseline and post-intervention assessments were conducted for general psychopathology, psychotic symptoms, global functioning, and symptom distress. Measures of change mechanisms were assessed before and after the respective treatment module. Participants' experiences were explored in feedback questionnaires and interviews. Recruitment, retention, and attendance rate met the pre-set feasibility benchmark of 80%. The intervention was well received by participants, who emphasised the group's clear structure, positive atmosphere, and helpful contents. Response rates were high and linear mixed models revealed significant medium-to-large time effects on all clinical outcomes. As expected, increase in hypothesised change mechanisms cognitive insight and decrease in cognitive fusion was found. However, the uncontrolled design limits interpreting clinical effects. The study provides evidence that an intervention based on a metacognitive model is feasible and acceptable for acute inpatients with psychosis. Positive results on clinical outcomes and change mechanisms warrant further exploration in a randomized controlled trial.

References
1.
Garety P, Waller H, Emsley R, Jolley S, Kuipers E, Bebbington P . Cognitive mechanisms of change in delusions: an experimental investigation targeting reasoning to effect change in paranoia. Schizophr Bull. 2014; 41(2):400-10. PMC: 4332945. DOI: 10.1093/schbul/sbu103. View

2.
Philippot P, Bouvard M, Baeyens C, Dethier V . Case conceptualization from a process-based and modular perspective: Rationale and application to mood and anxiety disorders. Clin Psychol Psychother. 2018; 26(2):175-190. DOI: 10.1002/cpp.2340. View

3.
McCutcheon R, Marques T, Howes O . Schizophrenia-An Overview. JAMA Psychiatry. 2019; 77(2):201-210. DOI: 10.1001/jamapsychiatry.2019.3360. View

4.
Jacobsen P, Peters E, Robinson E, Chadwick P . Mindfulness-based crisis interventions (MBCI) for psychosis within acute inpatient psychiatric settings; a feasibility randomised controlled trial. BMC Psychiatry. 2020; 20(1):193. PMC: 7191699. DOI: 10.1186/s12888-020-02608-x. View

5.
Moritz S, Veckenstedt R, Bohn F, Hottenrott B, Scheu F, Randjbar S . Complementary group Metacognitive Training (MCT) reduces delusional ideation in schizophrenia. Schizophr Res. 2013; 151(1-3):61-9. DOI: 10.1016/j.schres.2013.10.007. View