Editorial: The Epigenetic Control of Transposable Elements in Development and in Diseases

Overview

Journal Front Genet

Date 2023 Sep 21

PMID 37732323

Authors

Jan Padeken

Michelle S Longworth

Luisa Di Stefano

Affiliations

Soon will be listed here.

References

Ardeljan D, Steranka J, Liu C, Li Z, Taylor M, Payer L . Cell fitness screens reveal a conflict between LINE-1 retrotransposition and DNA replication. Nat Struct Mol Biol. 2020; 27(2):168-178. PMC: 7080318. DOI: 10.1038/s41594-020-0372-1. View

Jachowicz J, Bing X, Pontabry J, Boskovic A, Rando O, Torres-Padilla M . LINE-1 activation after fertilization regulates global chromatin accessibility in the early mouse embryo. Nat Genet. 2017; 49(10):1502-1510. DOI: 10.1038/ng.3945. View

Macfarlan T, Gifford W, Driscoll S, Lettieri K, Rowe H, Bonanomi D . Embryonic stem cell potency fluctuates with endogenous retrovirus activity. Nature. 2012; 487(7405):57-63. PMC: 3395470. DOI: 10.1038/nature11244. View

Macfarlan T, Gifford W, Agarwal S, Driscoll S, Lettieri K, Wang J . Endogenous retroviruses and neighboring genes are coordinately repressed by LSD1/KDM1A. Genes Dev. 2011; 25(6):594-607. PMC: 3059833. DOI: 10.1101/gad.2008511. View

Zhao K, Du J, Peng Y, Li P, Wang S, Wang Y . LINE1 contributes to autoimmunity through both RIG-I- and MDA5-mediated RNA sensing pathways. J Autoimmun. 2018; 90:105-115. DOI: 10.1016/j.jaut.2018.02.007. View

Ancelin K, Syx L, Borensztein M, Ranisavljevic N, Vassilev I, Briseno-Roa L . Maternal LSD1/KDM1A is an essential regulator of chromatin and transcription landscapes during zygotic genome activation. Elife. 2016; 5. PMC: 4829419. DOI: 10.7554/eLife.08851. View

Lepesant J, Iampietro C, Galeota E, Auge B, Aguirrenbengoa M, Merce C . A dual role of dLsd1 in oogenesis: regulating developmental genes and repressing transposons. Nucleic Acids Res. 2019; 48(3):1206-1224. PMC: 7026653. DOI: 10.1093/nar/gkz1142. View

Heinrich M, Purcell C, Pruijssers A, Zhao Y, Spurlock 3rd C, Sriram S . Endogenous double-stranded Alu RNA elements stimulate IFN-responses in relapsing remitting multiple sclerosis. J Autoimmun. 2019; 100:40-51. PMC: 6513682. DOI: 10.1016/j.jaut.2019.02.003. View

Simon M, Van Meter M, Ablaeva J, Ke Z, Gonzalez R, Taguchi T . LINE1 Derepression in Aged Wild-Type and SIRT6-Deficient Mice Drives Inflammation. Cell Metab. 2019; 29(4):871-885.e5. PMC: 6449196. DOI: 10.1016/j.cmet.2019.02.014. View

10.

McCullers T, Steiniger M . Transposable elements in . Mob Genet Elements. 2017; 7(3):1-18. PMC: 5443660. DOI: 10.1080/2159256X.2017.1318201. View

11.

Cuellar T, Herzner A, Zhang X, Goyal Y, Watanabe C, Friedman B . Silencing of retrotransposons by SETDB1 inhibits the interferon response in acute myeloid leukemia. J Cell Biol. 2017; 216(11):3535-3549. PMC: 5674883. DOI: 10.1083/jcb.201612160. View

12.

Yang F, Quan Z, Huang H, He M, Liu X, Cai T . Ovaries absent links dLsd1 to HP1a for local H3K4 demethylation required for heterochromatic gene silencing. Elife. 2019; 8. PMC: 6335052. DOI: 10.7554/eLife.40806. View

13.

Sheng W, LaFleur M, Nguyen T, Chen S, Chakravarthy A, Conway J . LSD1 Ablation Stimulates Anti-tumor Immunity and Enables Checkpoint Blockade. Cell. 2018; 174(3):549-563.e19. PMC: 6063761. DOI: 10.1016/j.cell.2018.05.052. View

14.

Percharde M, Lin C, Yin Y, Guan J, Peixoto G, Bulut-Karslioglu A . A LINE1-Nucleolin Partnership Regulates Early Development and ESC Identity. Cell. 2018; 174(2):391-405.e19. PMC: 6046266. DOI: 10.1016/j.cell.2018.05.043. View