The Effect of Benzyl Alcohol on the Voltage-Current Characteristics of Tethered Lipid Bilayers

Overview

Journal J Membr Biol

Date 2023 Sep 20

PMID 37728833

Authors

Hadeel Alobeedallah

Bruce Cornell

Mohammed Ghazal

Hans Coster

Affiliations

Soon will be listed here.

Abstract

In this study a lipid bilayer membrane model was used in which the bilayer is tethered to a solid substrate with molecular tethers. Voltage-current (V-I) measurements of the tethered bilayer membranes (tBLM) and tBLM with benzyl alcohol (BZA) incorporated in their structures, were measured using triangular voltage ramps of 0-500 mV. The temperature dependence of the conductance deduced from the V-I measurements are described. An evaluation of the activation energies for electrical conductance showed that BZA decreased the activation/ Born energies for ionic conduction of tethered lipid membranes. It is concluded that BZA increased the average pore radius of the tBLM.

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