Expanding Our Grasp of Two-component Signaling in

Overview

Journal J Bacteriol

Publisher American Society for Microbiology

Specialty Microbiology

Date 2023 Sep 20

PMID 37728603

Authors

Orlando Berumen Alvarez

Erin B Purcell

Affiliations

Soon will be listed here.

Abstract

The intestinal pathogen encodes roughly 50 TCS, but very few have been characterized in terms of their activating signals or their regulatory roles. A. G. Pannullo, B. R. Zbylicki, and C. D. Ellermeier (J Bacteriol 205:e00164-23, 2023, https://doi.org/10.1128/jb.00164-23) have identified both for the novel TCD DraRS. DraRS responds to antibiotics that target lipid-II molecules in the bacterial cell envelope, and regulates the production of a novel glycolipid necessary for bacitracin and daptomycin resistance in .

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