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A Case of Disseminated Coccidioidomycosis and Immune Reconstitution Inflammatory Syndrome (IRIS) in a Patient with HIV/AIDS

Overview
Journal IDCases
Specialty Infectious Diseases
Date 2023 Sep 20
PMID 37727860
Authors
Samantha R Kaplan
Amutha Rajagopal
Edward R Cachay
Robert Deiss
Affiliations
Soon will be listed here.
Abstract

Coccidioidomycosis is a fungal infection endemic to the southwestern United States and Central/South America, and its range is expanding with the warming climate. People with HIV/AIDS are at increased risk of developing disseminated infection, and furthermore are at risk for developing immune reconstitution inflammatory syndrome (IRIS) if they are initiating or re-initiating anti-retroviral therapy (ART). There have been few cases of coccidioidomycosis-related IRIS reported in the literature, and there is no clear guidance on treatment. We present a case of paradoxical IRIS in a patient with AIDS who clinically improved after initiating corticosteroids.

Citing Articles

immune reconstitution inflammatory syndrome (IRIS) in advanced HIV - An evidence-based summary.

Pal D, Rupali P IDCases. 2024; 36:e01957.

PMID: 38699522 PMC: 11063501. DOI: 10.1016/j.idcr.2024.e01957.

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