Dandelion Flower-fabricated Ag Nanoparticles Versus Synthetic Ones with Characterization and Determination of Photocatalytic, Antioxidant, Antibacterial, and α-glucosidase Inhibitory Activities

Overview

Journal Sci Rep

Specialty Science

Date 2023 Sep 18

PMID 37723218

Authors

Soheil Yousefzadeh-Valendeh

Mohammad Fattahi

Behvar Asghari

Zeinab Alizadeh

Affiliations

Soon will be listed here.

Abstract

In the present work, Silver nanoparticles (AgNPs) were fabricated through the dandelion flower hydroalcoholic extract, and their properties were characterized by FTIR, XRD, UV visible, SEM, and EDX. The results demonstrated that the average diameter of the green fabricated AgNPs is 45-55 nm (G-AgNPs). The antioxidant, antimicrobial, antidiabetic, and photocatalytic properties of G-AgNPs were compared with two commercially available different diameter sizes (20 and 80-100 nm) of AgNPs (C-AgNPs1- and C-AgNPs2, respectively). The sample's capacity for antioxidants was evaluated by DPPH free radical scavenging method. The consequences showed that G-AgNPs have higher radical scavenging activity (47.8%) than C-AgNPs2 (39.49%) and C-AgNPs1 (33.91%). To investigate the photocatalytic property, methylene blue dye was used. The results displayed that G-AgNPs is an effective photo-catalyst compared to C-AgNPs2 and C-AgNPs1, which respectively have an inhibition potential of 75.22, 51.94, and 56.65%. Also, the antimicrobial capacity of nanoparticles was assayed against, the gram-negative Escherichia coli and gram-positive Staphylococcus aureus bacteria. The results indicated that G-AgNPs could effectively inhibit the growth of both bacteria, compared to C-AgNPs1 and C-AgNPs2. Finally, G-AgNPs exhibited a considerable α-glucosidase enzyme inhibitory effect (88.37%) in comparison with C-AgNPs1 (61.7%) and C-AgNPs2 (50.5%).

Citing Articles

Green nanoparticles synthesized from damask rose petals: Evaluation of their antioxidant, antimicrobial, anti-diabetic, anti-Alzheimer, and photocatalytic properties.

Alizadeh Z, Fattahi M, Farokhzad A, Asghari B, Yousefzadeh-Valendeh S, Alipour H Heliyon. 2025; 11(4):e42557.

PMID: 40028576 PMC: 11869098. DOI: 10.1016/j.heliyon.2025.e42557.

Biosynthesis and characterization of iron oxide nanoparticles fabricated using cell-free supernatant of Pseudomonas fluorescens for antibacterial, antifungal, antioxidant, and photocatalytic applications.

Ashrafi-Saiedlou S, Rasouli-Sadaghiani M, Fattahi M, Ghosta Y Sci Rep. 2025; 15(1):1018.

PMID: 39762412 PMC: 11704013. DOI: 10.1038/s41598-024-84974-0.

References

He X, Deng H, Hwang H . The current application of nanotechnology in food and agriculture. J Food Drug Anal. 2019; 27(1):1-21. PMC: 9298627. DOI: 10.1016/j.jfda.2018.12.002. View

Avula B, Wang Y, Smillie T, Fu X, Li X, Mabusela W . Quantitative determination of flavonoids and cycloartanol glycosides from aerial parts of Sutherlandia frutescens (L.) R. BR. by using LC-UV/ELSD methods and confirmation by using LC-MS method. J Pharm Biomed Anal. 2010; 52(2):173-80. PMC: 3437656. DOI: 10.1016/j.jpba.2010.01.010. View

Ovais M, Khalil A, Ayaz M, Ahmad I, Nethi S, Mukherjee S . Biosynthesis of Metal Nanoparticles via Microbial Enzymes: A Mechanistic Approach. Int J Mol Sci. 2018; 19(12). PMC: 6321641. DOI: 10.3390/ijms19124100. View

Gulcin I . Antioxidants and antioxidant methods: an updated overview. Arch Toxicol. 2020; 94(3):651-715. DOI: 10.1007/s00204-020-02689-3. View

Konappa N, Udayashankar A, Dhamodaran N, Krishnamurthy S, Jagannath S, Uzma F . Ameliorated Antibacterial and Antioxidant Properties by Mediated Green Synthesis of Silver Nanoparticles. Biomolecules. 2021; 11(4). PMC: 8066458. DOI: 10.3390/biom11040535. View

Naidi S, Harunsani M, Tan A, Khan M . Green-synthesized CeO nanoparticles for photocatalytic, antimicrobial, antioxidant and cytotoxicity activities. J Mater Chem B. 2021; 9(28):5599-5620. DOI: 10.1039/d1tb00248a. View

Rafi Shaik M, Albalawi G, Khan S, Khan M, Adil S, Kuniyil M . "Miswak" Based Green Synthesis of Silver Nanoparticles: Evaluation and Comparison of Their Microbicidal Activities with the Chemical Synthesis. Molecules. 2016; 21(11). PMC: 6274424. DOI: 10.3390/molecules21111478. View

Mitri J, Hamdy O . Diabetes medications and body weight. Expert Opin Drug Saf. 2009; 8(5):573-84. DOI: 10.1517/14740330903081725. View

Astafieva A, Enyenihi A, Rogozhin E, Kozlov S, Grishin E, Odintsova T . Novel proline-hydroxyproline glycopeptides from the dandelion (Taraxacum officinale Wigg.) flowers: de novo sequencing and biological activity. Plant Sci. 2015; 238:323-9. DOI: 10.1016/j.plantsci.2015.07.002. View

10.

Bunaciu A, Udristioiu E, Aboul-Enein H . X-ray diffraction: instrumentation and applications. Crit Rev Anal Chem. 2015; 45(4):289-99. DOI: 10.1080/10408347.2014.949616. View

11.

Turunc E, Kahraman O, Binzet R . Green synthesis of silver nanoparticles using pollen extract: Characterization, assessment of their electrochemical and antioxidant activities. Anal Biochem. 2021; 621:114123. DOI: 10.1016/j.ab.2021.114123. View

12.

Kong J, Yu S . Fourier transform infrared spectroscopic analysis of protein secondary structures. Acta Biochim Biophys Sin (Shanghai). 2007; 39(8):549-59. DOI: 10.1111/j.1745-7270.2007.00320.x. View

13.

Ulagesan S, Nam T, Choi Y . Biogenic preparation and characterization of Pyropia yezoensis silver nanoparticles (P.y AgNPs) and their antibacterial activity against Pseudomonas aeruginosa. Bioprocess Biosyst Eng. 2020; 44(3):443-452. DOI: 10.1007/s00449-020-02454-x. View

14.

Ajitha B, Reddy Y, Sreedhara Reddy P . Biosynthesis of silver nanoparticles using Plectranthus amboinicus leaf extract and its antimicrobial activity. Spectrochim Acta A Mol Biomol Spectrosc. 2014; 128:257-62. DOI: 10.1016/j.saa.2014.02.105. View

15.

Velmurugan P, Shim J, Kamala-Kannan S, Lee K, Balachandar V, Oh B . Crystallization of silver through reduction process using Elaeis guineensis biosolid extract. Biotechnol Prog. 2011; 27(1):273-9. DOI: 10.1002/btpr.511. View

16.

Thirunavoukkarasu M, Balaji U, Behera S, Panda P, Mishra B . Biosynthesis of silver nanoparticle from leaf extract of Desmodium gangeticum (L.) DC. and its biomedical potential. Spectrochim Acta A Mol Biomol Spectrosc. 2013; 116:424-7. DOI: 10.1016/j.saa.2013.07.033. View

17.

Uddin I . Mechanistic approach to study conjugation of nanoparticles for biomedical applications. Spectrochim Acta A Mol Biomol Spectrosc. 2018; 202:238-243. DOI: 10.1016/j.saa.2018.05.042. View

18.

Hayat P, Khan I, Rehman A, Jamil T, Hayat A, Rehman M . Myogenesis and Analysis of Antimicrobial Potential of Silver Nanoparticles (AgNPs) against Pathogenic Bacteria. Molecules. 2023; 28(2). PMC: 9863364. DOI: 10.3390/molecules28020637. View

19.

Halliwell B . Oxidants and human disease: some new concepts. FASEB J. 1987; 1(5):358-64. View

20.

Mohanta Y, Panda S, Jayabalan R, Sharma N, Bastia A, Mohanta T . Antimicrobial, Antioxidant and Cytotoxic Activity of Silver Nanoparticles Synthesized by Leaf Extract of (Roxb.). Front Mol Biosci. 2017; 4:14. PMC: 5355429. DOI: 10.3389/fmolb.2017.00014. View