A Model of the Effect of Outer Hair Cell Motility on Cochlear Vibrations

Overview

Journal Hear Res

Specialty Otorhinolaryngology

Date 1986 Jan 1

PMID 3771375

Citations 6

Authors

C D Geisler

Affiliations

Soon will be listed here.

Abstract

A model of cochlear function is presented in which deformation forces within outer hair cells are assumed to occur in synchronized response to generator potentials. Assuming a 90 degree phase lag between the generator potentials and the deformation forces, it is shown that the forces act to reduce cochlear-partition damping and thus increase frequency selectivity. A number of other experimentally observed phenomena, such as the effects of efferent-fiber stimulation and electrical polarization, can also be accounted for with this model.

Citing Articles

In vivo outer hair cell length changes expose the active process in the cochlea.

Zha D, Chen F, Ramamoorthy S, Fridberger A, Choudhury N, Jacques S PLoS One. 2012; 7(4):e32757.

PMID: 22496736 PMC: 3322117. DOI: 10.1371/journal.pone.0032757.

Power efficiency of outer hair cell somatic electromotility.

Rabbitt R, Clifford S, Breneman K, Farrell B, Brownell W PLoS Comput Biol. 2009; 5(7):e1000444.

PMID: 19629162 PMC: 2705677. DOI: 10.1371/journal.pcbi.1000444.

Measurement of the mechanical properties of isolated tectorial membrane using atomic force microscopy.

Gueta R, Barlam D, Shneck R, Rousso I Proc Natl Acad Sci U S A. 2006; 103(40):14790-5.

PMID: 17001011 PMC: 1595430. DOI: 10.1073/pnas.0603429103.

Mechanics of the mammalian cochlea.

Robles L, Ruggero M Physiol Rev. 2001; 81(3):1305-52.

PMID: 11427697 PMC: 3590856. DOI: 10.1152/physrev.2001.81.3.1305.

A fast motile response in guinea-pig outer hair cells: the cellular basis of the cochlear amplifier.

Ashmore J J Physiol. 1987; 388:323-47.

PMID: 3656195 PMC: 1192551. DOI: 10.1113/jphysiol.1987.sp016617.