Editorial: Mechanisms of Action of Natural Antisense Transcripts on the Post-transcriptional Regulation of Sense Protein Coding Gene Expression During Development and in Cancer

Overview

Journal Front Mol Biosci

Specialty Biology

Date 2023 Sep 15

PMID 37711390

Authors

Tominori Kimura

Gian Gaetano Tartaglia

Affiliations

Soon will be listed here.

References

Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M . Antisense transcription in the mammalian transcriptome. Science. 2005; 309(5740):1564-6. DOI: 10.1126/science.1112009. View

Zhang Y, Liu X, Liu Q, Wei L . Genome-wide in silico identification and analysis of cis natural antisense transcripts (cis-NATs) in ten species. Nucleic Acids Res. 2006; 34(12):3465-75. PMC: 1524920. DOI: 10.1093/nar/gkl473. View

Lee R, Feinbaum R, Ambros V . The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14. Cell. 1993; 75(5):843-54. DOI: 10.1016/0092-8674(93)90529-y. View

Wightman B, Ha I, Ruvkun G . Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans. Cell. 1993; 75(5):855-62. DOI: 10.1016/0092-8674(93)90530-4. View

Jadaliha M, Gholamalamdari O, Tang W, Zhang Y, Petracovici A, Hao Q . A natural antisense lncRNA controls breast cancer progression by promoting tumor suppressor gene mRNA stability. PLoS Genet. 2018; 14(11):e1007802. PMC: 6289468. DOI: 10.1371/journal.pgen.1007802. View

Suzuki S, Yuan H, Hirata-Tsuchiya S, Yoshida K, Sato A, Nemoto E . DMP-1 promoter-associated antisense strand non-coding RNA, panRNA-DMP-1, physically associates with EGFR to repress EGF-induced squamous cell carcinoma migration. Mol Cell Biochem. 2021; 476(4):1673-1690. DOI: 10.1007/s11010-020-04046-5. View

Simone R, Javad F, Emmett W, Wilkins O, Almeida F, Barahona-Torres N . MIR-NATs repress MAPT translation and aid proteostasis in neurodegeneration. Nature. 2021; 594(7861):117-123. PMC: 7610982. DOI: 10.1038/s41586-021-03556-6. View

Wang C, Li J, Zhou C, Ma C, Wang D, Wo L . Long non-coding RNA ARHGAP5-AS1 inhibits migration of breast cancer cell via stabilizing SMAD7 protein. Breast Cancer Res Treat. 2021; 189(3):607-619. PMC: 8505316. DOI: 10.1007/s10549-021-06286-5. View

He Y, Vogelstein B, Velculescu V, Papadopoulos N, Kinzler K . The antisense transcriptomes of human cells. Science. 2008; 322(5909):1855-7. PMC: 2824178. DOI: 10.1126/science.1163853. View

10.

Zhang B, Zhang M, Yang Y, Li Q, Yu J, Zhu S . Targeting KDM4A-AS1 represses AR/AR-Vs deubiquitination and enhances enzalutamide response in CRPC. Oncogene. 2021; 41(3):387-399. PMC: 8755543. DOI: 10.1038/s41388-021-02103-x. View

11.

Pu J, Zhang Y, Wang A, Qin Z, Zhuo C, Li W . ADORA2A-AS1 Restricts Hepatocellular Carcinoma Progression Binding HuR and Repressing FSCN1/AKT Axis. Front Oncol. 2021; 11:754835. PMC: 8558402. DOI: 10.3389/fonc.2021.754835. View

12.

Chowdhary A, Satagopam V, Schneider R . Long Non-coding RNAs: Mechanisms, Experimental, and Computational Approaches in Identification, Characterization, and Their Biomarker Potential in Cancer. Front Genet. 2021; 12:649619. PMC: 8281131. DOI: 10.3389/fgene.2021.649619. View

13.

Podbevsek P, Fasolo F, Bon C, Cimatti L, Reisser S, Carninci P . Structural determinants of the SINE B2 element embedded in the long non-coding RNA activator of translation AS Uchl1. Sci Rep. 2018; 8(1):3189. PMC: 5816658. DOI: 10.1038/s41598-017-14908-6. View

14.

Nishizawa M, Ikeya Y, Okumura T, Kimura T . Post-transcriptional inducible gene regulation by natural antisense RNA. Front Biosci (Landmark Ed). 2015; 20(1):1-36. DOI: 10.2741/4297. View