Clinical Course and Optical Coherence Tomography of Ocular Angiostrongyliasis: A Case Report

Overview

Journal J Curr Ophthalmol

Date 2023 Sep 8

PMID 37680295

Authors

Kanin Luangsawang

Veeraphatra Wongsantimeth

Sirinan Treeyawedkul

Affiliations

Soon will be listed here.

Abstract

Purpose: To report the clinical course and optical coherence tomography (OCT) findings of ocular angiostrongyliasis.

Methods: A 36-year-old female with a history of ingesting regular raw freshwater shrimp and other raw food presented with acute unilateral painless visual loss in the right eye. Her right eye's best-corrected visual acuity (BCVA) was 1 ft of the count finger. Fundus examination showed vitritis, generalized retinal pigment epithelial alteration, and a moving roundworm in the vitreous at the 6 o'clock position. Macular OCT of her right eye showed thinning of the retina, loss of the external limiting membrane and ellipsoid zone, subretinal hyper-reflective material clumping, and hyper-reflective foci at the superficial choroidal layer.

Results: The patient was administered oral and topical prednisolone. The roundworm, identified as , was wholly extracted from the vitreous using a 23G sclerotomy port and pars plana vitrectomy. The final BCVA was 1 ft of the count finger.

Conclusion: This case report describes an infrequent presentation and illustrates the clinical course and OCT findings of ocular angiostrongyliasis.

References

Feng Y, Nawa Y, Sawanyavisuth K, Lv Z, Wu Z . Comprehensive review of ocular angiostrongyliasis with special reference to optic neuritis. Korean J Parasitol. 2014; 51(6):613-9. PMC: 3916447. DOI: 10.3347/kjp.2013.51.6.613. View

Diao Z, Wang J, Qi H, Li X, Zheng X, Yin C . Human ocular angiostrongyliasis: a literature review. Trop Doct. 2011; 41(2):76-8. DOI: 10.1258/td.2010.100294. View

Mazzeo T, Motta M, Curi A . Diffuse unilateral subacute neuroretinitis: review article. J Ophthalmic Inflamm Infect. 2019; 9(1):23. PMC: 6934636. DOI: 10.1186/s12348-019-0191-x. View

Berbel R, Casella A, Souza E, Farah M . Evaluation of patients with diffuse unilateral subacute neuroretinitis by spectral domain optical coherence tomography with enhanced depth imaging. Clin Ophthalmol. 2014; 8:1081-7. PMC: 4051808. DOI: 10.2147/OPTH.S60302. View

Gomes A, Garcia C, de Souza Segundo P, de Amorim Garcia Filho C, Garcia A . Optic coherence tomography in a patient with diffuse unilateral subacute neuroretinitis. Arq Bras Oftalmol. 2009; 72(2):185-8. DOI: 10.1590/s0004-27492009000200010. View

Eamsobhana P, Tungtrongchitr A, Wanachiwanawin D, Yong H . Immunochromatographic test for rapid serological diagnosis of human angiostrongyliasis. Int J Infect Dis. 2018; 73:69-71. DOI: 10.1016/j.ijid.2018.06.005. View

Sanguansak T, Angkawinijwong T, Ratanapakorn T, Intapan P, Sinawat S, Yospaiboon Y . Ocular angiostrongyliasis: clinical study of three cases. Eye (Lond). 2008; 22(11):1446-8. DOI: 10.1038/eye.2008.135. View

Ansdell V, Kramer K, McMillan J, Gosnell W, Murphy G, Meyer B . Guidelines for the diagnosis and treatment of neuroangiostrongyliasis: updated recommendations. Parasitology. 2020; 148(2):227-233. PMC: 7887556. DOI: 10.1017/S0031182020001262. View

Somboonpatarakun C, Intapan P, Sadaow L, Rodpai R, Sanpool O, Maleewong W . Development of an immunochromatographic device to detect antibodies for rapid diagnosis of human angiostrongyliasis. Parasitology. 2019; 147(2):194-198. PMC: 10317634. DOI: 10.1017/S0031182019001495. View

10.

Garcia Filho C, Soares A, Penha F, Garcia C . Spectral domain optical coherence tomography in diffuse unilateral subacute neuroretinitis. J Ophthalmol. 2011; 2011:285296. PMC: 3155787. DOI: 10.1155/2011/285296. View

11.

Sinawat S, Trisakul T, Choi S, Morley M, Sinawat S, Yospaiboon Y . Ocular angiostrongyliasis in Thailand: a retrospective analysis over two decades. Clin Ophthalmol. 2019; 13:1027-1031. PMC: 6592067. DOI: 10.2147/OPTH.S204380. View

12.

Kwon E, Ferguson T, Park S, Manuzak A, Qvarnstrom Y, Morgan S . A severe case of Angiostrongylus eosinophilic meningitis with encephalitis and neurologic sequelae in Hawa'i. Hawaii J Med Public Health. 2013; 72(6 Suppl 2):41-5. PMC: 3689496. View