» Articles » PMID: 37679589

Recent Advances in 3D Printable Conductive Hydrogel Inks for Neural Engineering

Overview
Journal Nano Converg
Specialty Biotechnology
Date 2023 Sep 7
PMID 37679589
Authors
Affiliations
Soon will be listed here.
Abstract

Recently, the 3D printing of conductive hydrogels has undergone remarkable advances in the fabrication of complex and functional structures. In the field of neural engineering, an increasing number of reports have been published on tissue engineering and bioelectronic approaches over the last few years. The convergence of 3D printing methods and electrically conducting hydrogels may create new clinical and therapeutic possibilities for precision regenerative medicine and implants. In this review, we summarize (i) advancements in preparation strategies for conductive materials, (ii) various printing techniques enabling the fabrication of electroconductive hydrogels, (iii) the required physicochemical properties of the printed constructs, (iv) their applications in bioelectronics and tissue regeneration for neural engineering, and (v) unconventional approaches and outlooks for the 3D printing of conductive hydrogels. This review provides technical insights into 3D printable conductive hydrogels and encompasses recent developments, specifically over the last few years of research in the neural engineering field.

Citing Articles

Conductive Biocomposite Made by Two-Photon Polymerization of Hydrogels Based on BSA and Carbon Nanotubes with Eosin-Y.

Savelyev M, Kuksin A, Murashko D, Otsupko E, Kurilova U, Selishchev S Gels. 2024; 10(11).

PMID: 39590067 PMC: 11594106. DOI: 10.3390/gels10110711.


Advances in materials and technologies for digital light processing 3D printing.

Nam J, Kim M Nano Converg. 2024; 11(1):45.

PMID: 39497012 PMC: 11534933. DOI: 10.1186/s40580-024-00452-3.


Simple and Cost-Effective Generation of 3D Cell Sheets and Spheroids Using Curvature-Controlled Paraffin Wax Substrates.

Kim H, Koo K, Kim C, Byun M, Park C, Son H Nano Converg. 2024; 11(1):44.

PMID: 39482392 PMC: 11527855. DOI: 10.1186/s40580-024-00451-4.


Recent Advances in Nanomaterials for Modulation of Stem Cell Differentiation and Its Therapeutic Applications.

Kim C, Koo K, Kim H, Kim T Biosensors (Basel). 2024; 14(8).

PMID: 39194636 PMC: 11352443. DOI: 10.3390/bios14080407.


Single/Multi-Network Conductive Hydrogels-A Review.

Hasan N, Bhuyan M, Jeong J Polymers (Basel). 2024; 16(14).

PMID: 39065347 PMC: 11281081. DOI: 10.3390/polym16142030.


References
1.
Wang C, Jiang X, Kim H, Zhang S, Zhou X, Chen Y . Flexible patch with printable and antibacterial conductive hydrogel electrodes for accelerated wound healing. Biomaterials. 2022; 285:121479. DOI: 10.1016/j.biomaterials.2022.121479. View

2.
Wu Y, Chen Y, Yan J, Quinn D, Dong P, Sawyer S . Fabrication of conductive gelatin methacrylate-polyaniline hydrogels. Acta Biomater. 2016; 33:122-30. DOI: 10.1016/j.actbio.2016.01.036. View

3.
Wang J, Li X, Song Y, Su Q, Xiaohalati X, Yang W . Injectable silk sericin scaffolds with programmable shape-memory property and neuro-differentiation-promoting activity for individualized brain repair of severe ischemic stroke. Bioact Mater. 2021; 6(7):1988-1999. PMC: 7786039. DOI: 10.1016/j.bioactmat.2020.12.017. View

4.
Zhang Y, Ali S, Dervishi E, Xu Y, Li Z, Casciano D . Cytotoxicity effects of graphene and single-wall carbon nanotubes in neural phaeochromocytoma-derived PC12 cells. ACS Nano. 2010; 4(6):3181-6. DOI: 10.1021/nn1007176. View

5.
Jeong J, Park J, Kim Y, Yang S, Jeong S, Lee J . Gamma Ray-Induced Polymerization and Cross-Linking for Optimization of PPy/PVP Hydrogel as Biomaterial. Polymers (Basel). 2020; 12(1). PMC: 7023038. DOI: 10.3390/polym12010111. View