Cell-targeted Vaccines: Implications for Adaptive Immunity

Overview

Journal Front Immunol

Specialty Allergy & Immunology

Date 2023 Sep 4

PMID 37662903

Authors

Trevor Ung

Nakisha S Rutledge

Adam M Weiss

Aaron P Esser-Kahn

Peter Deak

Affiliations

Soon will be listed here.

Abstract

Recent advancements in immunology and chemistry have facilitated advancements in targeted vaccine technology. Targeting specific cell types, tissue locations, or receptors can allow for modulation of the adaptive immune response to vaccines. This review provides an overview of cellular targets of vaccines, suggests methods of targeting and downstream effects on immune responses, and summarizes general trends in the literature. Understanding the relationships between vaccine targets and subsequent adaptive immune responses is critical for effective vaccine design. This knowledge could facilitate design of more effective, disease-specialized vaccines.

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