Analysis of Congenital Heart Disease Research: Mapping Impact, Production and Global Collaboration

Overview

Journal Heliyon

Specialty Social Sciences

Date 2023 Aug 31

PMID 37649838

Authors

J Pierre Zila-Velasque

Pamela Grados-Espinoza

W Samir Cubas

Mario Diaz-Barrera

Josmel Pacheco-Mendoza

Affiliations

Soon will be listed here.

Abstract

Background: Congenital heart disease (CHD) is a severe childhood health problem worldwide. This study analyzes the scientific production on CHD published in Scopus during the last decade.

Methods: This study assessed the research on CHD conducted during the 2011-2020 period. Indexed publications were identified using a list of keywords consisting of MeSH (Medical Subject Heading) and Emtree (EMBASE) terms for the category "Congenital Heart Defects." The studies obtained were analyzed using the SciVal platform, and the production, impact, and collaboration indicators were considered. Additionally, an analysis of co-occurrence between countries and keywords was carried out with the VOSviewer software.

Results: The study found 8934 articles on CHD. A growing trend was observed during the last decade. The distribution of the scientific production at the international level shows that most publications are from the United States, China, and the United Kingdom, whereas Latin American countries have the lowest production. The articles analyzed contain a total of 89,835 citations. Most studies are published in high-impact journals (Q1), with 3273 studies corresponding to 39.3% of the total production analyzed. In the keyword analysis, we found five areas investigated.

Conclusions: Scientific production has shown sustained growth in the past years. Increased scientific production in specific research areas may have helped decrease morbimortality due to CHD.

Citing Articles

Epidemiological characterization of congenital heart disease at different altitudes in Ecuador: a four-year retrospective study in a pediatric referral hospital.

Izquierdo-Condoy J, Arias-Rodriguez F, Diaz-Chamba W, Mena-Norona D, Toaquiza L, Espin-Sambache B Front Public Health. 2025; 13:1497253.

PMID: 39944066 PMC: 11813749. DOI: 10.3389/fpubh.2025.1497253.

Adverse Drug Reactions in Children with Congenital Heart Disease: A Scoping Review.

Toni E, Ayatollahi H, Abbaszadeh R, Fotuhi Siahpirani A Paediatr Drugs. 2024; 26(5):519-553.

PMID: 39044096 DOI: 10.1007/s40272-024-00644-8.

References

Spector L, Menk J, Knight J, McCracken C, Thomas A, Vinocur J . Trends in Long-Term Mortality After Congenital Heart Surgery. J Am Coll Cardiol. 2018; 71(21):2434-2446. PMC: 5978758. DOI: 10.1016/j.jacc.2018.03.491. View

de Lima C, Paiva B, Dos Santos Neto M, Hui D, Perez-Cruz P, Zimmermann C . The Impact of International Research Collaborations on the Citation Metrics and the Scientific Potential of South American Palliative Care Research: Bibliometric Analysis. Ann Glob Health. 2021; 87(1):32. PMC: 8015710. DOI: 10.5334/aogh.3158. View

Yasuhara J, Garg V . Genetics of congenital heart disease: a narrative review of recent advances and clinical implications. Transl Pediatr. 2021; 10(9):2366-2386. PMC: 8506053. DOI: 10.21037/tp-21-297. View

Lopez-Verges S, Urbani B, Fernandez Rivas D, Kaur-Ghumaan S, Coussens A, Moronta-Barrios F . Mitigating losses: how scientific organisations can help address the impact of the COVID-19 pandemic on early-career researchers. Humanit Soc Sci Commun. 2021; 8(1):284. PMC: 8646015. DOI: 10.1057/s41599-021-00944-1. View

Galdini A, Fesslova V, Gaeta G, Candiani M, Pozzoni M, Chiarello C . Prevalence of Congenital Heart Defects in Pregnancies Conceived by Assisted Reproductive Technology: A Cohort Study. J Clin Med. 2021; 10(22). PMC: 8621349. DOI: 10.3390/jcm10225363. View

. NCD Countdown 2030: worldwide trends in non-communicable disease mortality and progress towards Sustainable Development Goal target 3.4. Lancet. 2018; 392(10152):1072-1088. DOI: 10.1016/S0140-6736(18)31992-5. View

Falagas M, Pitsouni E, Malietzis G, Pappas G . Comparison of PubMed, Scopus, Web of Science, and Google Scholar: strengths and weaknesses. FASEB J. 2007; 22(2):338-42. DOI: 10.1096/fj.07-9492LSF. View

Farhat T, Abdul-Sater Z, Obeid M, Arabi M, Diab K, Masri S . Research in congenital heart disease: a comparative bibliometric analysis between developing and developed countries. Pediatr Cardiol. 2012; 34(2):375-82. DOI: 10.1007/s00246-012-0466-6. View

Tchervenkov C, Jacobs J, Bernier P, Stellin G, Kurosawa H, Mavroudis C . The improvement of care for paediatric and congenital cardiac disease across the World: a challenge for the World Society for Pediatric and Congenital Heart Surgery. Cardiol Young. 2008; 18 Suppl 2:63-9. DOI: 10.1017/S1047951108002801. View

10.

Rajiah P, Mak C, Dubinksy T, Dighe M . Ultrasound of fetal cardiac anomalies. AJR Am J Roentgenol. 2011; 197(4):W747-60. DOI: 10.2214/AJR.10.7287. View

11.

Shuaib W, Khan M, Shahid H, Valdes E, Alweis R . Bibliometric analysis of the top 100 cited cardiovascular articles. Am J Cardiol. 2015; 115(7):972-81. DOI: 10.1016/j.amjcard.2015.01.029. View

12.

Mazboudi M, Ben Abdelaziz A . Medical research productivity of Lebanon: a bibliometric study of papers indexed in Medline, 1985-2004. Tunis Med. 2010; 88(8):579-85. View

13.

To M, Jones J, Emara M, Jadad A . Are reports of randomized controlled trials improving over time? A systematic review of 284 articles published in high-impact general and specialized medical journals. PLoS One. 2014; 8(12):e84779. PMC: 3877340. DOI: 10.1371/journal.pone.0084779. View

14.

Yu Z, Li D, Sun L, Zhao X, Chang H, Cui L . Long-term trends in the incidence of congenital anomalies in Central China from 1997 to 2019. Public Health. 2022; 203:47-52. DOI: 10.1016/j.puhe.2021.12.007. View

15.

Al-Aqeel S, Mendes A, Taisir H, Fernandez-Llimos F . International collaboration in pharmacy practice research: A bibliometric analysis. Res Social Adm Pharm. 2020; 16(11):1513-1518. DOI: 10.1016/j.sapharm.2020.05.019. View

16.

Stallings E, Isenburg J, Aggarwal D, Lupo P, Oster M, Shephard H . Prevalence of critical congenital heart defects and selected co-occurring congenital anomalies, 2014-2018: A U.S. population-based study. Birth Defects Res. 2022; 114(2):45-56. PMC: 8915134. DOI: 10.1002/bdr2.1980. View

17.

Liu Y, Chen S, Zuhlke L, Black G, Choy M, Li N . Global birth prevalence of congenital heart defects 1970-2017: updated systematic review and meta-analysis of 260 studies. Int J Epidemiol. 2019; 48(2):455-463. PMC: 6469300. DOI: 10.1093/ije/dyz009. View

18.

McManus C, Neves A, Maranhao A, Filho A, Martins Santana J . International collaboration in Brazilian science: financing and impact. Scientometrics. 2020; 125(3):2745-2772. PMC: 7547822. DOI: 10.1007/s11192-020-03728-7. View

19.

Su Z, Zou Z, Hay S, Liu Y, Li S, Chen H . Global, regional, and national time trends in mortality for congenital heart disease, 1990-2019: An age-period-cohort analysis for the Global Burden of Disease 2019 study. EClinicalMedicine. 2022; 43:101249. PMC: 8760503. DOI: 10.1016/j.eclinm.2021.101249. View

20.

Orwat M, Kempny A, Bauer U, Gatzoulis M, Baumgartner H, Diller G . The importance of national and international collaboration in adult congenital heart disease: A network analysis of research output. Int J Cardiol. 2015; 195:155-62. DOI: 10.1016/j.ijcard.2015.05.116. View