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BRUCH MEMBRANE RUPTURE AND CHOROIDAL NEOVASCULARIZATION COMPLICATING EXTENSIVE MACULAR ATROPHY WITH PSEUDODRUSEN-LIKE APPEARANCE: A CASE REPORT

Overview
Journal Retin Cases Brief Rep
Specialty Ophthalmology
Date 2023 Aug 29
PMID 37643042
Authors
Dario Romano
Leonardo Colombo
Paolo Maltese
Matteo Bertelli
Luca M Rossetti
Affiliations
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Abstract

Purpose: To describe a case of extensive macular atrophy with pseudodrusen-like appearance complicated by Bruch membrane rupture and choroidal neovascularization, treated with intravitreal injection of an antivascular endothelial growth factor drug.

Methods: A 54-year-old woman, affected by extensive macular atrophy with pseudodrusen-like appearance, has developed Bruch membrane rupture and choroidal neovascularization. This report discusses the development of the disease and the improvement after a single intravitreal injection of Avastin.

Results: After treatment, the visual acuity increased from 20/400 to 20/200; clinical and anatomical improvement remained stable with a 2-month follow-up.

Conclusion: Extensive macular atrophy with pseudodrusen-like appearance could be complicated by Bruch membrane rupture and subsequent choroidal neovascularization. Antivascular endothelial growth factor intravitreal injection could have beneficial effects on this entity, but concern could raise in respect of possible increase of chorioretinal atrophy.

Citing Articles

Extensive macular atrophy with pseudodrusen-like appearance: comprehensive review of the literature.

Carla M, Giannuzzi F, Boselli F, Crincoli E, Rizzo S Graefes Arch Clin Exp Ophthalmol. 2024; 262(10):3085-3097.

PMID: 39133226 PMC: 11458735. DOI: 10.1007/s00417-024-06600-z.

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