Epigenetics in Neurological and Psychiatric Disorders: A Comprehensive Review of Current Understanding and Future Perspectives

Overview

Journal Cureus

Specialty Biomedical Engineering

Date 2023 Aug 25

PMID 37622055

Authors

Han Grezenko

Chukwuyem Ekhator

Nkechi U Nwabugwu

Harshita Ganga

Maryam Affaf

Ali M Abdelaziz

Abdur Rehman

Abdullah Shehryar

Fatima A Abbasi

Sophia B Bellegarde

Abdul Saboor Khaliq

Affiliations

Soon will be listed here.

Abstract

The burgeoning field of epigenetics offers transformative insights into the complex landscape of neurological and psychiatric disorders. By unraveling the intricate interplay between genetic, epigenetic, environmental, and lifestyle factors, this comprehensive review highlights the multifaceted nature of mental health. The exploration reveals the potential of epigenetic modifications to revolutionize our understanding, diagnosis, treatment, and prevention of these disorders. Emphasizing the importance of multidisciplinary collaborations, large-scale studies, technological advancements, and ethical considerations, the review asserts the promise of epigenetics as a vital tool for personalized medicine, early intervention, and public health strategies. While acknowledging the challenges in a still-emerging field, the review paints an optimistic picture of epigenetics as a groundbreaking approach that can reshape mental healthcare, offering hope for those affected by neurological and psychiatric conditions. The future trajectory of the field relies on interdisciplinary efforts, ethical diligence, innovative technologies, and translating scientific insights into real-world applications, thereby unlocking the vast potential of epigenetics in mental health.

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