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Biomarkers of Aging and Relevant Evaluation Techniques: A Comprehensive Review

Overview
Journal Aging Dis
Specialty Geriatrics
Date 2023 Aug 23
PMID 37611906
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Abstract

The risk of developing chronic illnesses and disabilities is increasing with age. To predict and prevent aging, biomarkers relevant to the aging process must be identified. This paper reviews the known molecular, cellular, and physiological biomarkers of aging. Moreover, we discuss the currently available technologies for identifying these biomarkers, and their applications and potential in aging research. We hope that this review will stimulate further research and innovation in this emerging and fast-growing field.

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References
1.
Holzscheck N, Falckenhayn C, Sohle J, Kristof B, Siegner R, Werner A . Modeling transcriptomic age using knowledge-primed artificial neural networks. NPJ Aging Mech Dis. 2021; 7(1):15. PMC: 8169742. DOI: 10.1038/s41514-021-00068-5. View

2.
Ali M, Archer D, Gorijala P, Western D, Timsina J, Fernandez M . Large multi-ethnic genetic analyses of amyloid imaging identify new genes for Alzheimer disease. Acta Neuropathol Commun. 2023; 11(1):68. PMC: 10134547. DOI: 10.1186/s40478-023-01563-4. View

3.
Preische O, Schultz S, Apel A, Kuhle J, Kaeser S, Barro C . Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer's disease. Nat Med. 2019; 25(2):277-283. PMC: 6367005. DOI: 10.1038/s41591-018-0304-3. View

4.
Chen R, Zhang K, Chen H, Zhao X, Wang J, Li L . Telomerase Deficiency Causes Alveolar Stem Cell Senescence-associated Low-grade Inflammation in Lungs. J Biol Chem. 2015; 290(52):30813-29. PMC: 4692211. DOI: 10.1074/jbc.M115.681619. View

5.
Benjamens S, Dhunnoo P, Mesko B . The state of artificial intelligence-based FDA-approved medical devices and algorithms: an online database. NPJ Digit Med. 2020; 3:118. PMC: 7486909. DOI: 10.1038/s41746-020-00324-0. View