Worldwide Status of Insecticide Resistance of and , Vectors of Arboviruses of Chikungunya, Dengue, Zika and Yellow Fever

Overview

Journal J Arthropod Borne Dis

Publisher Tehran University of Medical Sciences

Date 2023 Aug 23

PMID 37609563

Authors

Tahereh Sadat Asgarian

Hassan Vatandoost

Ahmad Ali Hanafi-Bojd

Fatemeh Nikpoor

Affiliations

Soon will be listed here.

Abstract

Background: Controlling of and , vectors of five important mosquito-borne diseases, is known as the most effective method to prevent the transmission of arboviruses to humans, but the emergence of insecticide resistance is threat for control and prevention of vector borne diseases. A better understanding of mosquito resistance to insecticides will help to develop more effective methods to control insecticide resistance in mosquito vectors.

Methods: Worldwide geographical distribution of insecticide resistance in and by the available papers and map of the data for carbamates, organochlorines, organophosphates, pyrethroids, microbial and insect growth regulator insecticides were reviewed. Article data published up to December 2022 were investigated by searching the following databases: "Google Scholar", "PubMed", "Scopus", "SID" and "Web of Knowledge".

Results: The results showed that the susceptibility and resistance status of and to insecticides in the world is very diverse.

Conclusion: Due to the importance of and in the transmission of mosquito-borne arboviruses, resistance management should be given more attention worldwide to prevent insecticide resistance in the arbovirus vector and replace the new approach for vector control.

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References

Chen C, Nazni W, Lee H, Sofian-Azirun M . Susceptibility of Aedes aegypti and Aedes albopictus to temephos in four study sites in Kuala Lumpur City Center and Selangor State, Malaysia. Trop Biomed. 2006; 22(2):207-16. View

Bhatt S, Gething P, Brady O, Messina J, Farlow A, Moyes C . The global distribution and burden of dengue. Nature. 2013; 496(7446):504-7. PMC: 3651993. DOI: 10.1038/nature12060. View

Chediak M, G Pimenta Jr F, Coelho G, Braga I, Lima J, Cavalcante K . Spatial and temporal country-wide survey of temephos resistance in Brazilian populations of Aedes aegypti. Mem Inst Oswaldo Cruz. 2016; 111(5):311-21. PMC: 4878300. DOI: 10.1590/0074-02760150409. View

Bengoa M, Eritja R, Delacour S, Miranda M, Sureda A, Lucientes J . First Data on Resistance to Pyrethroids in Wild Populations of Aedes albopictus from Spain. J Am Mosq Control Assoc. 2017; 33(3):246-249. DOI: 10.2987/17-6636R.1. View

Marcombe S, Carron A, Darriet F, Etienne M, Agnew P, Tolosa M . Reduced efficacy of pyrethroid space sprays for dengue control in an area of Martinique with pyrethroid resistance. Am J Trop Med Hyg. 2009; 80(5):745-51. View

Wong P, Li M, Chong C, Ng L, Tan C . Aedes (Stegomyia) albopictus (Skuse): a potential vector of Zika virus in Singapore. PLoS Negl Trop Dis. 2013; 7(8):e2348. PMC: 3731215. DOI: 10.1371/journal.pntd.0002348. View

Granada Y, Mejia-Jaramillo A, Strode C, Triana-Chavez O . A Point Mutation V419L in the Sodium Channel Gene from Natural Populations of Aedes aegypti Is Involved in Resistance to λ-Cyhalothrin in Colombia. Insects. 2018; 9(1). PMC: 5872288. DOI: 10.3390/insects9010023. View

Mukhtar M, Ibrahim S . Temporal Evaluation of Insecticide Resistance in Populations of the Major Arboviral Vector from Northern Nigeria. Insects. 2022; 13(2). PMC: 8876019. DOI: 10.3390/insects13020187. View

Rodriguez M, Bisset J, Fernandez D . Levels of insecticide resistance and resistance mechanisms in Aedes aegypti from some Latin American countries. J Am Mosq Control Assoc. 2008; 23(4):420-9. DOI: 10.2987/5588.1. View

10.

Flores A, Ponce G, Silva B, Gutierrez S, Bobadilla C, Lopez B . Wide spread cross resistance to pyrethroids in Aedes aegypti (Diptera: Culicidae) from Veracruz state Mexico. J Econ Entomol. 2013; 106(2):959-69. PMC: 3980443. DOI: 10.1603/ec12284. View

11.

Liu H, Cupp E, Guo A, Liu N . Insecticide resistance in Alabama and Florida mosquito strains of Aedes albopictus. J Med Entomol. 2004; 41(5):946-52. DOI: 10.1603/0022-2585-41.5.946. View

12.

Ping L, Yatiman R, Gek L . Susceptibility of adult field strains of Aedes aegypti and Aedes albopictus in Singapore to pirimiphos-methyl and permethrin. J Am Mosq Control Assoc. 2001; 17(2):144-6. View

13.

Endersby-Harshman N, Wuliandari J, Harshman L, Frohn V, Johnson B, Ritchie S . Pyrethroid Susceptibility Has Been Maintained in the Dengue Vector, Aedes aegypti (Diptera: Culicidae), in Queensland, Australia. J Med Entomol. 2017; 54(6):1649-1658. DOI: 10.1093/jme/tjx145. View

14.

Demok S, Endersby-Harshman N, Vinit R, Timinao L, Robinson L, Susapu M . Insecticide resistance status of Aedes aegypti and Aedes albopictus mosquitoes in Papua New Guinea. Parasit Vectors. 2019; 12(1):333. PMC: 6609403. DOI: 10.1186/s13071-019-3585-6. View

15.

Dusfour I, Thalmensy V, Gaborit P, Issaly J, Carinci R, Girod R . Multiple insecticide resistance in Aedes aegypti (Diptera: Culicidae) populations compromises the effectiveness of dengue vector control in French Guiana. Mem Inst Oswaldo Cruz. 2011; 106(3):346-52. DOI: 10.1590/s0074-02762011000300015. View

16.

Kongmee M, Prabaripai A, Akratanakul P, Bangs M, Chareonviriyaphap T . Behavioral responses of Aedes aegypti (Diptera: Culicidae) exposed to deltamethrin and possible implications for disease control. J Med Entomol. 2004; 41(6):1055-63. DOI: 10.1603/0022-2585-41.6.1055. View

17.

Garcia G, David M, Martins A, Maciel-de-Freitas R, Linss J, Araujo S . The impact of insecticide applications on the dynamics of resistance: The case of four Aedes aegypti populations from different Brazilian regions. PLoS Negl Trop Dis. 2018; 12(2):e0006227. PMC: 5833288. DOI: 10.1371/journal.pntd.0006227. View

18.

Yiguan W, Xin L, Chengling L, Su T, Jianchao J, Yuhong G . A Survey of Insecticide Resistance in Aedes albopictus (Diptera: Culicidae) During a 2014 Dengue Fever Outbreak in Guangzhou, China. J Econ Entomol. 2016; 110(1):239-244. DOI: 10.1093/jee/tow254. View

19.

Francis S, Saavedra-Rodriguez K, Perera R, Paine M, Black 4th W, Delgoda R . Insecticide resistance to permethrin and malathion and associated mechanisms in Aedes aegypti mosquitoes from St. Andrew Jamaica. PLoS One. 2017; 12(6):e0179673. PMC: 5484480. DOI: 10.1371/journal.pone.0179673. View

20.

Liu N . Insecticide resistance in mosquitoes: impact, mechanisms, and research directions. Annu Rev Entomol. 2015; 60:537-59. DOI: 10.1146/annurev-ento-010814-020828. View