Hypochloruria Associated with Hypovolemia

Hypochloruria is proposed as an indicator of hypovolemia in ICU non cardiac patients. Twelve of 13 patients presenting with Clu less than or equal to 20 mmol X l-1 and Nau greater than or equal to 20 mmol X l-1 or twice the Clu value had a CVP less than or equal to 0 mmHg. This pattern occurred in those with a metabolic alkalosis or acidosis, renal insufficiency or normal renal function, in the presence or absence of dopamine and/or diuretic administration and with or without controlled ventilation. Hypochloruria may be a better indicator of hypovolemia than a low urinary Na in ICU patients.