Case Report: First Report on Human Infection by Tick-borne in the Amazon Region of Ecuador

Overview

Journal Front Public Health

Specialty Public Health

Date 2023 Aug 21

PMID 37601195

Authors

Manuel Calvopina

Maria Montesdeoca-Andrade

Carlos Bastidas-Caldes

Sandra Enriquez

Richar Rodriguez-Hidalgo

Dayana Aguilar-Rodriguez

Philip Cooper

Affiliations

Soon will be listed here.

Abstract

Babesiosis is a protozoan disease acquired by the bite of different species of ticks. More than 100 spp. infect wild and domestic animals worldwide, but only a few have been documented to infect humans. Generally, babesiosis is asymptomatic in immunocompetent persons; however, in immunocompromised can be life-threatening. A 13-year-old boy from the Amazon region presented with a 3-month evolution of fever, chills, general malaise, and arthralgia accompanied by anemia and jaundice. In the last 4 years was diagnosed with chronic kidney failure. By nested-PCR using 18S RNA ribosomal gene as target and DNA sequencing, the phylogenetic analysis showed as the causative agent in the blood. Treatment with oral quinine plus clindamycin for six continuous weeks was effective with no relapse occurring during 12 months of follow-up. This is the second human case in Ecuador but the first caused by the zoonotic which confirms the existence of active transmission that should alert public health decision-making authorities on the emergence of this zoonosis and the need for research to determine strategies to reduce tick exposure.

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