» Articles » PMID: 37587391

SARS-CoV-2 Vaccination in Children and Adolescents with and Without Type 1 Diabetes Mellitus

Overview
Journal Endocrine
Specialty Endocrinology
Date 2023 Aug 16
PMID 37587391
Authors
Affiliations
Soon will be listed here.
Abstract

Adults with Diabetes Mellitus (DM) have increased risk of severe clinical presentation during COVID-19 infection, while children and adolescents with type 1 diabetes (T1D) have the same mild clinical course as their healthy peers, especially those with optimal glycemic control. The present review focuses on the necessity of COVID-19 vaccination among children and adolescents with T1D, and also in their non-diabetic peers. The efficacy and safety of COVID-19 vaccines are also discussed, as well as their various side-effects, ranging from common mild to very rare and serious ones. Furthermore, the results of COVID-19 vaccination of adolescents with and without T1D are reported, as well as the efficacy and concerns about childhood vaccination. It is concluded that patients with DM of all age groups should maintain optimal diabetic control in order to avoid glycemic deterioration during COVID-19 infection. Furthermore, despite the very rare and serious complications of COVID-19 vaccines, vaccination against COVID-19 is recommended for children and adolescents with T1D to prevent glycemic deterioration and rare but serious complications of COVID-19 infection.

References
1.
Podhorecka M, Pyszora A, Wozniewicz A, Husejko J, Kedziora-Kornatowska K . Health and Protective Measures for Seniors during the COVID-19 Pandemic in the Opinion of Polish Society. Int J Environ Res Public Health. 2021; 18(17). PMC: 8430700. DOI: 10.3390/ijerph18179230. View

2.
Pal R, Bhadada S, Misra A . COVID-19 vaccination in patients with diabetes mellitus: Current concepts, uncertainties and challenges. Diabetes Metab Syndr. 2021; 15(2):505-508. PMC: 7904463. DOI: 10.1016/j.dsx.2021.02.026. View

3.
Kusuma Boddu S, Aurangabadkar G, Kuchay M . New onset diabetes, type 1 diabetes and COVID-19. Diabetes Metab Syndr. 2021; 14(6):2211-2217. PMC: 7669477. DOI: 10.1016/j.dsx.2020.11.012. View

4.
Brufsky A . Hyperglycemia, hydroxychloroquine, and the COVID-19 pandemic. J Med Virol. 2020; 92(7):770-775. PMC: 7262330. DOI: 10.1002/jmv.25887. View

5.
Sen S, Chakraborty R, Kalita P, Pathak M . Diabetes mellitus and COVID-19: Understanding the association in light of current evidence. World J Clin Cases. 2021; 9(28):8327-8339. PMC: 8554438. DOI: 10.12998/wjcc.v9.i28.8327. View