En Bloc Resection of Bladder Tumour: the Rebirth of Past Through Reminiscence

Overview

Journal World J Urol

Specialty Urology

Date 2023 Aug 16

PMID 37584691

Authors

Jeremy Yuen-Chun Teoh

David DAndrea

Andrea Gallioli

Takafumi Yanagisawa

Steven MacLennan

Rossella Nicoletti

Ng Chi Fai

Davide Maffei

Rodolfo Hurle

Lukas Lusuardi

Bernard Malavaud

Jun Miki

Mario Kramer

Hugh Mostafid

Dmitry Enikeev

Marek Babjuk

Alberto Breda

Shahrokh Shariat

Paolo Gontero

Thomas Herrmann

Affiliations

Soon will be listed here.

Abstract

Purpose: To learn about the history and development of en bloc resection of bladder tumour (ERBT), and to discuss its future directions in managing bladder cancer.

Methods: In this narrative review, we summarised the history and early development of ERBT, previous attempts in overcoming the tumour size limitation, consolidative effort in standardising the ERBT procedure, emerging evidence in ERBT, evolving concepts in treating large bladder tumours, and the future directions of ERBT.

Results: Since the first report on ERBT in 1980, there has been tremendous advancement in terms of its technique, energy modalities and tumour retrieval methods. In 2020, the international consensus statement on ERBT has been developed and it serves as a standard reference for urologists to practise ERBT. Recently, high-quality evidence on ERBT has been emerging. Of note, the EB-StaR study showed that ERBT led to a reduction in 1-year recurrence rate from 38.1 to 28.5%. An individual patient data meta-analysis is currently underway, and it will be instrumental in defining the true value of ERBT in treating non-muscle-invasive bladder cancer. For large bladder tumours, modified approaches of ERBT should be accepted, as the quality of resection is more important than a mere removal of tumour in one piece. The global ERBT registry has been launched to study the value of ERBT in a real-world setting.

Conclusion: ERBT is a promising surgical technique in treating bladder cancer and it has gained increasing interest globally. It is about time for us to embrace this technique in our clinical practice.

Citing Articles

A single-center retrospective comparison of pT1 substaging methods in bladder cancer.

Klager J, Koeller M, Oszwald A, Wasinger G, DAndrea D, Comperat E Virchows Arch. 2024; .

PMID: 39222123 DOI: 10.1007/s00428-024-03907-4.

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