A Case of Familial Appendiceal Neuroendocrine Tumor
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Abstract
The risk of developing appendiceal neuroendocrine tumor (aNET) may be attributed to multiple factors. A familial clustering is found in less than 1% of the cases. We report the case of a 25-year-old woman who initially presented with a clinical presentation of acute appendicitis and was subsequently diagnosed with aNET by histopathological examination after an emergency appendectomy. While revealing the result to the patient, she was found to have a positive family history of appendiceal carcinoid tumor. Although rare and only found in 1% of the cases, aNET found in family history should raise the suspicion of neuroendocrine tumors in other family members.
References
1.
Hassan M, Phan A, Li D, Dagohoy C, Leary C, Yao J
. Risk factors associated with neuroendocrine tumors: A U.S.-based case-control study. Int J Cancer. 2008; 123(4):867-73.
DOI: 10.1002/ijc.23529.
View
2.
Alkhayyat M, Saleh M, Coronado W, Abureesh M, Zmaili M, Qapaja T
. Epidemiology of neuroendocrine tumors of the appendix in the USA: a population-based national study (2014-2019). Ann Gastroenterol. 2021; 34(5):713-720.
PMC: 8375642.
DOI: 10.20524/aog.2021.0643.
View
3.
Taal B, Visser O
. Epidemiology of neuroendocrine tumours. Neuroendocrinology. 2004; 80 Suppl 1:3-7.
DOI: 10.1159/000080731.
View
4.
Popa O, Taban S, Pantea S, Plopeanu A, Barna R, Cornianu M
. The new WHO classification of gastrointestinal neuroendocrine tumors and immunohistochemical expression of somatostatin receptor 2 and 5. Exp Ther Med. 2021; 22(4):1179.
PMC: 8406677.
DOI: 10.3892/etm.2021.10613.
View
5.
de Nova J, Hernando J, Sampedro Nunez M, Vazquez Benitez G, Trivino Ibanez E, Del Olmo Garcia M
. Management of incidentally discovered appendiceal neuroendocrine tumors after an appendicectomy. World J Gastroenterol. 2022; 28(13):1304-1314.
PMC: 9099182.
DOI: 10.3748/wjg.v28.i13.1304.
View