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Fabrication of PLA-Based Electrospun Nanofibers Reinforced with ZnO Nanoparticles and Degradation Study

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Date 2023 Aug 12
PMID 37570553
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Abstract

In this work, electrospun nanofibers based on polylactic acid, PLA, reinforced with ZnO nanoparticles have been studied, considering the growing importance of electrospun mats based on biopolymers for their applications in different fields. Specifically, electrospun nanofibers based on PLA have been prepared by adding ZnO nanoparticles at different concentrations, such as 0.5, 1, 3, 5, 10 and 20 wt%, with respect to the polymer matrix. The materials have been characterized in terms of their morphological, mechanical, and thermal properties, finding 3 wt% as the best concentration to produce PLA nanofibers reinforced with ZnO nanoparticles. In addition, hydrolytic degradation in phosphate buffer solution (PBS) was carried out to study the effect of ZnO nanoparticles on the degradation behavior of PLA-based electrospun nanofiber mats, obtaining an acceleration in the degradation of the PLA electrospun mat.

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References
1.
Canales D, Pinones N, Saavedra M, Loyo C, Palza H, Peponi L . Fabrication and assessment of bifunctional electrospun poly(l-lactic acid) scaffolds with bioglass and zinc oxide nanoparticles for bone tissue engineering. Int J Biol Macromol. 2022; 228:78-88. DOI: 10.1016/j.ijbiomac.2022.12.195. View

2.
Ferrandez-Montero A, Lieblich M, Gonzalez-Carrasco J, Benavente R, Lorenzo V, Detsch R . Development of biocompatible and fully bioabsorbable PLA/Mg films for tissue regeneration applications. Acta Biomater. 2019; 98:114-124. DOI: 10.1016/j.actbio.2019.05.026. View

3.
Xue J, Wu T, Dai Y, Xia Y . Electrospinning and Electrospun Nanofibers: Methods, Materials, and Applications. Chem Rev. 2019; 119(8):5298-5415. PMC: 6589095. DOI: 10.1021/acs.chemrev.8b00593. View

4.
Liu H, Gough C, Deng Q, Gu Z, Wang F, Hu X . Recent Advances in Electrospun Sustainable Composites for Biomedical, Environmental, Energy, and Packaging Applications. Int J Mol Sci. 2020; 21(11). PMC: 7312508. DOI: 10.3390/ijms21114019. View

5.
Shamsah A, Cartmell S, Richardson S, Bosworth L . Material Characterization of PCL:PLLA Electrospun Fibers Following Six Months Degradation In Vitro. Polymers (Basel). 2020; 12(3). PMC: 7183275. DOI: 10.3390/polym12030700. View