Combined Exposure to PM and PM in Reductions of Physiological Development Among Preterm Birth: a Retrospective Study from 2014 to 2017 in China

Overview

Journal Front Public Health

Specialty Public Health

Date 2023 Aug 11

PMID 37564430

Authors

Bo Hu

Jie Tang

Guangtao Xu

Dongliang Shao

Huafei Huang

Jintong Li

Huan Chen

Jie Chen

Liangjin Zhu

Shipiao Chen

Bin Shen

Limin Jin

Long Xu

Affiliations

Soon will be listed here.

Abstract

Background: Preterm birth (PTB) has been linked with ambient particulate matter (PM) exposure. However, data are limited between physiological development of PTB and PM exposure.

Methods: Trimester and season-specific PM exposure including PM and PM was collected from Jiaxing between January 2014 and December 2017. Information about parents and 3,054 PTB (gestational age < 37 weeks) outcomes such as weight (g), head circumference (cm), chest circumference (cm), height (cm) and Apgar 5 score were obtained from birth records. We used generalized linear models to assess the relationship between PTB physiological developmental indices and PM, PM and their combined exposures. A binary logistic regression model was performed to assess the association between exposures and low birth weight (LBW, < 2,500 g).

Results: Results showed that there were 75.5% of low birth weight (LBW) infants in PTB. Decreased PM and PM levels were found in Jiaxing from 2014 to 2017, with a higher PM level than PM each year. During the entire pregnancy, the highest median concentration of PM and PM was in winter (61.65 ± 0.24 vs. 91.65 ± 0.29 μg/m) followed by autumn, spring and summer, with statistical differences in trimester-specific stages. After adjusting for several potential factors, we found a 10 μg/m increase in joint exposure of PM and PM during the entire pregnancy associated with reduced 0.02 week (95%CI: -0.05, -0.01) in gestational age, 7.9 g (95%CI: -13.71, -2.28) in birth weight, 0.8 cm in height (95%CI: -0.16, -0.02), 0.05 cm (95%CI: -0.08, - 0.01) in head circumference, and 0.3 (95%CI: -0.04, -0.02) in Apgar 5 score, except for the chest circumference. Trimester-specific exposure of PM and PM sometimes showed an opposite effect on Additionally, PM (OR = 1.37, 95%CI: 1.11, 1.68) was correlated with LBW.

Conclusion: Findings in this study suggest a combined impact of fine particulate matter exposure on neonatal development, which adds to the current understanding of PTB risk and health.

References

Ma R, Luo Y, Wang J, Zhou Y, Sun H, Ren X . Ten-year time trends in preterm birth during a sociodemographic transition period: a retrospective cohort study in Shenzhen, China. BMJ Open. 2020; 10(10):e037266. PMC: 7577040. DOI: 10.1136/bmjopen-2020-037266. View

Vinikoor-Imler L, Davis J, Meyer R, Messer L, Luben T . Associations between prenatal exposure to air pollution, small for gestational age, and term low birthweight in a state-wide birth cohort. Environ Res. 2014; 132:132-9. DOI: 10.1016/j.envres.2014.03.040. View

Wylie B, Kishashu Y, Matechi E, Zhou Z, Coull B, Abioye A . Maternal exposure to carbon monoxide and fine particulate matter during pregnancy in an urban Tanzanian cohort. Indoor Air. 2016; 27(1):136-146. PMC: 4987269. DOI: 10.1111/ina.12289. View

Chen M, Chiu C, Yuan C, Liao Y, Guo S . Influence of Environmental Tobacco Smoke and Air Pollution on Fetal Growth: A Prospective Study. Int J Environ Res Public Health. 2020; 17(15). PMC: 7432534. DOI: 10.3390/ijerph17155319. View

Zou Z, Liu W, Huang C, Cai J, Fu Q, Sun C . Gestational exposures to outdoor air pollutants in relation to low birth weight: A retrospective observational study. Environ Res. 2020; 193:110354. DOI: 10.1016/j.envres.2020.110354. View

Wei H, Baktash M, Zhang R, Wang X, Zhang M, Jiang S . Associations of maternal exposure to fine particulate matter constituents during pregnancy with Apgar score and duration of labor: A retrospective study in Guangzhou, China, 2012-2017. Chemosphere. 2020; 273:128442. DOI: 10.1016/j.chemosphere.2020.128442. View

Arroyo V, Diaz J, Salvador P, Linares C . Impact of air pollution on low birth weight in Spain: An approach to a National Level Study. Environ Res. 2019; 171:69-79. DOI: 10.1016/j.envres.2019.01.030. View

Han Y, Wang W, Wang X, Dong T, van Donkelaar A, Martin R . Prenatal exposure to fine particles, premature rupture of membranes and gestational age: A prospective cohort study. Environ Int. 2020; 145:106146. DOI: 10.1016/j.envint.2020.106146. View

Arinola G, Dutta A, Oluwole O, Olopade C . Household Air Pollution, Levels of Micronutrients and Heavy Metals in Cord and Maternal Blood, and Pregnancy Outcomes. Int J Environ Res Public Health. 2018; 15(12). PMC: 6313792. DOI: 10.3390/ijerph15122891. View

10.

Qian Z, Liang S, Yang S, Trevathan E, Huang Z, Yang R . Ambient air pollution and preterm birth: A prospective birth cohort study in Wuhan, China. Int J Hyg Environ Health. 2015; 219(2):195-203. DOI: 10.1016/j.ijheh.2015.11.003. View

11.

Qiao P, Zhao Y, Cai J, van Donkelaar A, Martin R, Ying H . Twin growth discordance in association with maternal exposure to fine particulate matter and its chemical constituents during late pregnancy. Environ Int. 2019; 133(Pt A):105148. DOI: 10.1016/j.envint.2019.105148. View

12.

Zhao Y, Wang P, Zhou Y, Xia B, Zhu Q, Ge W . Prenatal fine particulate matter exposure, placental DNA methylation changes, and fetal growth. Environ Int. 2020; 147:106313. DOI: 10.1016/j.envint.2020.106313. View

13.

Li Z, Tang Y, Song X, Lazar L, Li Z, Zhao J . Impact of ambient PM on adverse birth outcome and potential molecular mechanism. Ecotoxicol Environ Saf. 2018; 169:248-254. DOI: 10.1016/j.ecoenv.2018.10.109. View

14.

Li S, Peng L, Wu X, Xu G, Cheng P, Hao J . Long-term impact of ambient air pollution on preterm birth in Xuzhou, China: a time series study. Environ Sci Pollut Res Int. 2021; 28(30):41039-41050. DOI: 10.1007/s11356-021-13621-2. View

15.

He L, Wu M, Wang D, Zhong Z . A study of the influence of regional environmental expenditure on air quality in China: the effectiveness of environmental policy. Environ Sci Pollut Res Int. 2017; 25(8):7454-7468. DOI: 10.1007/s11356-017-1033-8. View

16.

Spears D, Dey S, Chowdhury S, Scovronick N, Vyas S, Apte J . The association of early-life exposure to ambient PM and later-childhood height-for-age in India: an observational study. Environ Health. 2019; 18(1):62. PMC: 6617650. DOI: 10.1186/s12940-019-0501-7. View

17.

Khalili R, Bartell S, Hu X, Liu Y, Chang H, Belanoff C . Early-life exposure to PM and risk of acute asthma clinical encounters among children in Massachusetts: a case-crossover analysis. Environ Health. 2018; 17(1):20. PMC: 5822480. DOI: 10.1186/s12940-018-0361-6. View

18.

Fiordelisi A, Piscitelli P, Trimarco B, Coscioni E, Iaccarino G, Sorriento D . The mechanisms of air pollution and particulate matter in cardiovascular diseases. Heart Fail Rev. 2017; 22(3):337-347. DOI: 10.1007/s10741-017-9606-7. View

19.

Ye H, Tang J, Luo L, Yang T, Fan K, Xu L . High-normal blood pressure (prehypertension) is associated with PM exposure in young adults. Environ Sci Pollut Res Int. 2022; 29(27):40701-40710. DOI: 10.1007/s11356-022-18862-3. View

20.

Wang J, Yang Q, Yang C, Cai Y, Xing T, Gao L . Smad3 promotes AKI sensitivity in diabetic mice via interaction with p53 and induction of NOX4-dependent ROS production. Redox Biol. 2020; 32:101479. PMC: 7058410. DOI: 10.1016/j.redox.2020.101479. View