» Articles » PMID: 37562280

Application of Femoral Nail, Reconstruction Locked Plate and Bone Morphogenic Protein - 7 in an Osteopetrosis Patient with a Recurrent Femoral Shaft Fracture: A Case Report

Overview
Specialty General Surgery
Date 2023 Aug 10
PMID 37562280
Authors
Affiliations
Soon will be listed here.
Abstract

Introduction And Importance: Femoral fractures are common in the patients with osteopetrosis and multiple treatment strategies have been described with varying results. However, there is a paucity of literature describing the treatment of recurrent fractures and subsequent deformity.

Case Presentation: We present detailed revision strategies and long-term follow-up results of a patient with osteopetrosis who suffered unsuccessful operative treatment using the plate-screw system (recurrent femoral shaft fracture and implant failure).

Clinical Discussion: The success of revision surgery of osteopetrosis is based on good preoperative planning, appropriate selection of fixation methods, and a meticulous approach during surgery. The combined application of the expert adolescent lateral femoral nail, the reconstruction locked plate, and bone morphogenic protein (BMP)-7 in this patient achieved good clinical results.

Conclusion: In the treatment of failed plated and recurrent osteopetrotic femoral shaft fractures, the combination of nails and plating presents an alternative, potentially more successful, revision strategy.

References
1.
Gandhi R, Salehi M, Davey J . Cemented bipolar hemiarthroplasty in osteoporosis for failed femoral neck fixation. Can J Surg. 2009; 52(3):E44-6. PMC: 2689733. View

2.
Zhang J, Liu H, Cai T, Lin Y, Wu J . Resistant distal femoral nonunion treated with combined nail/plate construct and reamer-irrigator-aspirator technique. J Int Med Res. 2023; 51(7):3000605231187945. PMC: 10387779. DOI: 10.1177/03000605231187945. View

3.
Benichou O, Laredo J, De Vernejoul M . Type II autosomal dominant osteopetrosis (Albers-Schönberg disease): clinical and radiological manifestations in 42 patients. Bone. 2000; 26(1):87-93. DOI: 10.1016/s8756-3282(99)00244-6. View

4.
Golden R, Rodriguez E . Management of subtrochanteric femur fractures with internal fixation and recombinant human bone morphogenetic protein-7 in a patient with osteopetrosis: a case report. J Med Case Rep. 2010; 4:142. PMC: 2887894. DOI: 10.1186/1752-1947-4-142. View

5.
Chawla A, Kwek E . Fractures in patients with osteopetrosis, insights from a single institution. Int Orthop. 2018; 43(6):1297-1302. DOI: 10.1007/s00264-018-4167-5. View