[S1 Guidelines for the Management of Postviral Conditions Using the Example of Post-COVID-19]

Overview

Journal Wien Klin Wochenschr

Publisher Springer

Specialty General Medicine

Date 2023 Aug 9

PMID 37555900

Authors

Susanne Rabady

Kathryn Hoffmann

Martin Aigner

Johann Altenberger

Markus Brose

Ursula Costa

Doris-Maria Denk-Linnert

Samuel Gruber

Florian Gotzinger

Raimund Helbok

Katharina Hufner

Rembert Koczulla

Katharina Kurz

Bernd Lamprecht

Stefan Leis

Judith Loffler

Christian A Muller

Hans Rittmannsberger

Paulus S Rommer

Paul Sator

Volker Strenger

Walter Struhal

Eva Untersmayr

Karin Vonbank

Johannes Wancata

Thomas Weber

Maria Wendler

Ralf-Harun Zwick

Affiliations

Soon will be listed here.

Abstract

These S1 guidelines are an updated and expanded version of the S1 guidelines on long COVID differential diagnostic and management strategies. They summarize the state of knowledge on postviral conditions like long/post COVID at the time of writing. Due to the dynamic nature of knowledge development, they are intended to be "living guidelines". The focus is on practical applicability at the level of primary care, which is understood to be the appropriate place for initial access and for primary care and treatment. The guidelines provide recommendations on the course of treatment, differential diagnostics of the most common symptoms that can result from infections like with SARS-CoV-2, treatment options, patient management and care, reintegration and rehabilitation. The guidelines have been developed through an interdisciplinary and interprofessional process and provide recommendations on interfaces and possibilities for collaboration.

Citing Articles

"A bit of a cough, tired, not very resilient - is that already Long-COVID?" perceptions and experiences of GPs with Long-COVID in year three of the pandemic. a qualitative interview study in Austria.

Wojczewski S, Mayrhofer M, Szabo N, Rabady S, Hoffmann K BMC Public Health. 2024; 24(1):3078.

PMID: 39511549 PMC: 11542353. DOI: 10.1186/s12889-024-20475-z.

Health care for patients with long COVID: a scoping review.

Curvelo R, Ribeiro A, Uehara S Rev Esc Enferm USP. 2024; 58:e20240056.

PMID: 39475394 PMC: 11524158. DOI: 10.1590/1980-220X-REEUSP-2024-0056en.

Barriers and facilitators of healthcare access for long COVID-19 patients in a universal healthcare system: qualitative evidence from Austria.

Gamillscheg P, Laszewska A, Kirchner S, Hoffmann K, Simon J, Mayer S Int J Equity Health. 2024; 23(1):220.

PMID: 39443935 PMC: 11515580. DOI: 10.1186/s12939-024-02302-4.

[Interdisciplinary, collaborative D-A-CH (Germany, Austria and Switzerland) consensus statement concerning the diagnostic and treatment of myalgic encephalomyelitis/chronic fatigue syndrome].

Hoffmann K, Hainzl A, Stingl M, Kurz K, Biesenbach B, Bammer C Wien Klin Wochenschr. 2024; 136(Suppl 5):103-123.

PMID: 38743348 PMC: 11093804. DOI: 10.1007/s00508-024-02372-y.

Management of cognitive impairment associated with post-COVID-19 syndrome: recommendations for primary care.

Zifko U, Guendling K, Seet R, Kasper S Front Pharmacol. 2024; 15:1338235.

PMID: 38711990 PMC: 11072190. DOI: 10.3389/fphar.2024.1338235.

References

Vultaggio A, Agache I, Akdis C, Akdis M, Bavbek S, Bossios A . Considerations on biologicals for patients with allergic disease in times of the COVID-19 pandemic: An EAACI statement. Allergy. 2020; 75(11):2764-2774. PMC: 7300800. DOI: 10.1111/all.14407. View

Dhawan R, Gopalan D, Howard L, Vicente A, Park M, Manalan K . Beyond the clot: perfusion imaging of the pulmonary vasculature after COVID-19. Lancet Respir Med. 2020; 9(1):107-116. PMC: 7833494. DOI: 10.1016/S2213-2600(20)30407-0. View

Fogh K, Larsen T, Hansen C, Hasselbalch R, Eriksen A, Bundgaard H . Self-Reported Long COVID and Its Association with the Presence of SARS-CoV-2 Antibodies in a Danish Cohort up to 12 Months after Infection. Microbiol Spectr. 2022; 10(6):e0253722. PMC: 9769646. DOI: 10.1128/spectrum.02537-22. View

Raveendran A, Jayadevan R, Sashidharan S . Long COVID: An overview. Diabetes Metab Syndr. 2021; 15(3):869-875. PMC: 8056514. DOI: 10.1016/j.dsx.2021.04.007. View

Bozkurt B, Coats A, Tsutsui H, Abdelhamid C, Adamopoulos S, Albert N . Universal definition and classification of heart failure: a report of the Heart Failure Society of America, Heart Failure Association of the European Society of Cardiology, Japanese Heart Failure Society and Writing Committee of the Universal.... Eur J Heart Fail. 2021; 23(3):352-380. DOI: 10.1002/ejhf.2115. View

Davis H, Assaf G, McCorkell L, Wei H, Low R, Reem Y . Characterizing long COVID in an international cohort: 7 months of symptoms and their impact. EClinicalMedicine. 2021; 38:101019. PMC: 8280690. DOI: 10.1016/j.eclinm.2021.101019. View

Whittaker E, Bamford A, Kenny J, Kaforou M, Jones C, Shah P . Clinical Characteristics of 58 Children With a Pediatric Inflammatory Multisystem Syndrome Temporally Associated With SARS-CoV-2. JAMA. 2020; 324(3):259-269. PMC: 7281356. DOI: 10.1001/jama.2020.10369. View

Jarius S, Pache F, Kortvelyessy P, Jelcic I, Stettner M, Franciotta D . Cerebrospinal fluid findings in COVID-19: a multicenter study of 150 lumbar punctures in 127 patients. J Neuroinflammation. 2022; 19(1):19. PMC: 8771621. DOI: 10.1186/s12974-021-02339-0. View

Wang E, Mao T, Klein J, Dai Y, Huck J, Jaycox J . Diverse functional autoantibodies in patients with COVID-19. Nature. 2021; 595(7866):283-288. DOI: 10.1038/s41586-021-03631-y. View

10.

Stevens S, Snell C, Stevens J, Keller B, Vanness J . Cardiopulmonary Exercise Test Methodology for Assessing Exertion Intolerance in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. Front Pediatr. 2018; 6:242. PMC: 6131594. DOI: 10.3389/fped.2018.00242. View

11.

Matta J, Wiernik E, Robineau O, Carrat F, Touvier M, Severi G . Association of Self-reported COVID-19 Infection and SARS-CoV-2 Serology Test Results With Persistent Physical Symptoms Among French Adults During the COVID-19 Pandemic. JAMA Intern Med. 2021; 182(1):19-25. PMC: 8576624. DOI: 10.1001/jamainternmed.2021.6454. View

12.

Elliott N, Martin R, Heron N, Elliott J, Grimstead D, Biswas A . Infographic. Graduated return to play guidance following COVID-19 infection. Br J Sports Med. 2020; 54(19):1174-1175. PMC: 7371566. DOI: 10.1136/bjsports-2020-102637. View

13.

McMahon D, Gallman A, Hruza G, Rosenbach M, Lipoff J, Desai S . Long COVID in the skin: a registry analysis of COVID-19 dermatological duration. Lancet Infect Dis. 2021; 21(3):313-314. PMC: 7836995. DOI: 10.1016/S1473-3099(20)30986-5. View

14.

van Campen C, Verheugt F, Rowe P, Visser F . Cerebral blood flow is reduced in ME/CFS during head-up tilt testing even in the absence of hypotension or tachycardia: A quantitative, controlled study using Doppler echography. Clin Neurophysiol Pract. 2020; 5:50-58. PMC: 7044650. DOI: 10.1016/j.cnp.2020.01.003. View

15.

Schweitzer F, Goereci Y, Franke C, Silling S, Bosl F, Maier F . Cerebrospinal Fluid Analysis Post-COVID-19 Is Not Suggestive of Persistent Central Nervous System Infection. Ann Neurol. 2021; 91(1):150-157. PMC: 8653324. DOI: 10.1002/ana.26262. View

16.

Fabbri V, Riefolo M, Lazzarotto T, Gabrielli L, Cenacchi G, Gallo C . COVID-19 and the Brain: The Neuropathological Italian Experience on 33 Adult Autopsies. Biomolecules. 2022; 12(5). PMC: 9138268. DOI: 10.3390/biom12050629. View

17.

Leo F, Bulau J, Semper H, Grohe C . Correlation of respiratory muscle function and cardiopulmonary exercise testing in post-acute COVID-19 syndrome. Infection. 2022; 51(2):527-530. PMC: 9379900. DOI: 10.1007/s15010-022-01899-4. View

18.

Astin R, Banerjee A, Baker M, Dani M, Ford E, Hull J . Long COVID: mechanisms, risk factors and recovery. Exp Physiol. 2022; 108(1):12-27. PMC: 10103775. DOI: 10.1113/EP090802. View

19.

Greenhalgh T, Knight M, ACourt C, Buxton M, Husain L . Management of post-acute covid-19 in primary care. BMJ. 2020; 370:m3026. DOI: 10.1136/bmj.m3026. View

20.

Sepulcri C, Dentone C, Mikulska M, Bruzzone B, Lai A, Fenoglio D . The Longest Persistence of Viable SARS-CoV-2 With Recurrence of Viremia and Relapsing Symptomatic COVID-19 in an Immunocompromised Patient-A Case Study. Open Forum Infect Dis. 2021; 8(11):ofab217. PMC: 8135455. DOI: 10.1093/ofid/ofab217. View