Proton Pump Inhibitors and the Risk of Acquiring a Penicillin Allergy Label
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Abstract
The negative consequences of having a penicillin allergy label are well established. Penicillin allergy de-labelling improves healthcare outcomes; however, less attention is paid to modifying risk factors leading to penicillin allergy development. In this propensity score-matched retrospective cohort study, we used a de-identified population-based database (TriNetX Research Network) and examined the 30-day risk of acquiring a penicillin allergy label in patients using proton pump inhibitors (PPIs). We demonstrated a higher risk of acquiring a penicillin allergy label among PPI users compared to controls.
References
1.
Pascal M, Perez-Gordo M, Caballero T, Escribese M, Lopez Longo M, Luengo O
. Microbiome and Allergic Diseases. Front Immunol. 2018; 9:1584.
PMC: 6056614.
DOI: 10.3389/fimmu.2018.01584.
View
2.
Trikha A, Baillargeon J, Kuo Y, Tan A, Pierson K, Sharma G
. Development of food allergies in patients with gastroesophageal reflux disease treated with gastric acid suppressive medications. Pediatr Allergy Immunol. 2013; 24(6):582-8.
PMC: 4528619.
DOI: 10.1111/pai.12103.
View
3.
Untersmayr E, Bakos N, Scholl I, Kundi M, Roth-Walter F, Szalai K
. Anti-ulcer drugs promote IgE formation toward dietary antigens in adult patients. FASEB J. 2005; 19(6):656-8.
DOI: 10.1096/fj.04-3170fje.
View
4.
. Drug allergy: an updated practice parameter. Ann Allergy Asthma Immunol. 2010; 105(4):259-273.
DOI: 10.1016/j.anai.2010.08.002.
View
5.
Shaker M, Khan D, Banerji A, Blumenthal K, Phillips E, Solensky R
. Drug allergy: A 2022 practice parameter update. J Allergy Clin Immunol. 2022; 150(6):1333-1393.
DOI: 10.1016/j.jaci.2022.08.028.
View